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chamomile tea
Chamomile tea contains bioactive compounds that bind to benzodiazepine and GABA receptors, promoting relaxation and reducing anxiety through central nervous system modulation.
Chamomile tea contains bioactive compounds that bind to benzodiazepine and GABA receptors, promoting relaxation and reducing anxiety through central nervous system modulation. Used for Anxiety and nervousness, Insomnia and sleep disturbances, Gastrointestinal discomfort and digestive support.
At a glance
| Generic name | chamomile tea |
|---|---|
| Sponsor | National Center for Complementary and Integrative Health (NCCIH) |
| Drug class | Herbal anxiolytic/sedative |
| Target | GABA receptors, benzodiazepine receptors |
| Modality | Small molecule |
| Therapeutic area | Neurology, Sleep Medicine, Gastroenterology |
| Phase | FDA-approved |
Mechanism of action
Chamomile contains flavonoids and other phytochemicals, particularly apigenin, which interact with GABAergic and benzodiazepine receptor systems in the brain. These interactions enhance inhibitory neurotransmission, leading to sedative, anxiolytic, and muscle-relaxant effects. Additionally, chamomile may modulate inflammatory pathways and possess antioxidant properties that contribute to its traditional use in promoting sleep and digestive comfort.
Approved indications
- Anxiety and nervousness
- Insomnia and sleep disturbances
- Gastrointestinal discomfort and digestive support
Common side effects
- Allergic reactions (rare, particularly in individuals with ragweed sensitivity)
- Drowsiness
- Headache
- Dizziness
Key clinical trials
- Synbiotic Supplement With Botanical Extracts for Gut Microbiota Balance in Irritable Bowel Syndrome (NA)
- Assessing the Impact of Herbal Supplement on Fatigue and Disease Activity in SLE: Results From an 8-Week Randomized Trial (NA)
- Aromatherapy Formulas for Sundowning and Sleep Quality in Patients With Dementia. (NA)
- Chamomile Gummies and Pediatric Dental Anxiety (PHASE2, PHASE3)
- Effects of Chamomile With L-theanine Beverage Among Young Women Experiencing Primary Dysmenorrhea (NA)
- Aromatherapy Applied to Intensive Care Nurses Effect on Fatigue and Sleep Quality (NA)
- A Post-market Study to Evaluate the Effects of Sodium Hyaluronate Based Eye Drops in Patients Affected by Dry Eye Disease (NA)
- Different Exercise Training Programs in University Students with Primary Dysmenorrhea (NA)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- chamomile tea CI brief — competitive landscape report
- chamomile tea updates RSS · CI watch RSS
- National Center for Complementary and Integrative Health (NCCIH) portfolio CI