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Cetylpyridinium Chloride Buccal Tablets

Peking University People's Hospital · FDA-approved active Small molecule

Cetylpyridinium chloride is a cationic antimicrobial agent that disrupts bacterial cell membranes and inhibits microbial growth in the oral cavity.

Cetylpyridinium chloride is a cationic antimicrobial agent that disrupts bacterial cell membranes and inhibits microbial growth in the oral cavity. Used for Oral antimicrobial therapy for minor oral infections and inflammation, Oral hygiene and antiseptic treatment.

At a glance

Generic nameCetylpyridinium Chloride Buccal Tablets
SponsorPeking University People's Hospital
Drug classQuaternary ammonium antimicrobial agent
TargetBacterial cell membrane
ModalitySmall molecule
Therapeutic areaOral/Dental
PhaseFDA-approved

Mechanism of action

Cetylpyridinium chloride (CPC) is a quaternary ammonium compound that acts as a broad-spectrum antimicrobial by binding to and disrupting bacterial cell membranes, leading to leakage of cellular contents and cell death. The buccal tablet formulation allows for prolonged local contact with oral tissues, providing sustained antimicrobial activity against oral pathogens. It is commonly used for oral hygiene and the treatment of minor oral infections and inflammation.

Approved indications

Common side effects

Key clinical trials

Primary sources

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SourceUsed for
ClinicalTrials.govTrial enrolment, design, endpoints, results