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Deacetoxycefotaxime (CEFETAMET)

Phase 2 active Small molecule

Deacetoxycefotaxime (generic name: CEFETAMET) is a cefetamet drug. It is currently in Phase 2 development.

Deacetoxycefotaxime works by inhibiting the bacterial enzyme responsible for cell wall synthesis, ultimately leading to cell lysis and death.

Deacetoxycefotaxime, also known as CEFETAMET, is a third-generation cephalosporin antibiotic belonging to the cefetamet drug class. It is a small molecule modality, but its current commercial status and approved indications are unknown. The pharmacokinetic properties of CEFETAMET include a half-life of 2.1 hours and bioavailability of 47%. As a cephalosporin antibiotic, it works by inhibiting bacterial cell wall synthesis, but its specific target is unknown. Further research is needed to determine its clinical utility and safety profile.

Likelihood of approval
17.3% vs 15.3% industry baseline
If approved by FDA: likely 2031–2034
Steps remaining: Phase 3 → NDA/BLA submission
Confidence: Medium
Why this estimate
  • Baseline phase 2 → approval rate +15.3pp
    Industry-wide phase 2 drugs reach approval ~15.3% of the time (BIO/Informa 2023 industry benchmark across all therapeutic areas).
  • Anti-infectives pathway favourability +2.0pp
    Microbiological endpoints + non-inferiority designs raise approval rates above baseline.
Predicted approval windows by jurisdiction (conditional on FDA approval)
Regulator Country Likely year Lag vs FDA
FDA US 2031–2034
EMA EU 2032–2035 +0.7 yr
MHRA GB 2032–2035 +0.7 yr
Health Canada CA 2032–2036 +0.9 yr
TGA AU 2032–2036 +1.2 yr
PMDA JP 2032–2036 +1.5 yr
NMPA CN 2033–2037 +2.3 yr
MFDS KR 2032–2036 +1.4 yr
CDSCO IN 2032–2037 +1.8 yr
ANVISA BR 2033–2037 +2.3 yr

Hover any row for the lag rationale. Lag estimates are reduced when the drug has FDA Breakthrough or EMA PRIME designation (sponsors file globally in parallel).

Estimate based on the BIO/Informa industry phase transition rates plus per-drug modifiers for therapeutic area, sponsor type, FDA designations, mechanism, and trial design. Per-jurisdiction lags from Tufts CSDD international approval studies. Not investment, clinical or regulatory advice. Methodology: /methodology#likelihood.

At a glance

Generic nameCEFETAMET
Drug classcefetamet
ModalitySmall molecule
Therapeutic areaInfectious Disease
PhasePhase 2

Mechanism of action

Imagine your body's cells are like buildings with walls. Bacteria have special machines that build these walls, and deacetoxycefotaxime blocks these machines, causing the walls to collapse and the bacteria to die.

Approved indications

No approved indications tracked.

Common side effects

No common side effects on file.

Key clinical trials

Primary sources

Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.

SourceUsed for
ClinicalTrials.govTrial enrolment, design, endpoints, results

Competitive intelligence

For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:

Frequently asked questions about Deacetoxycefotaxime

What is Deacetoxycefotaxime?

Deacetoxycefotaxime (CEFETAMET) is a cefetamet drug.

How does Deacetoxycefotaxime work?

Deacetoxycefotaxime works by inhibiting the bacterial enzyme responsible for cell wall synthesis, ultimately leading to cell lysis and death.

What is the generic name of Deacetoxycefotaxime?

CEFETAMET is the generic (nonproprietary) name of Deacetoxycefotaxime.

What drug class is Deacetoxycefotaxime in?

Deacetoxycefotaxime belongs to the cefetamet class. See all cefetamet drugs at /class/cefetamet.

What development phase is Deacetoxycefotaxime in?

Deacetoxycefotaxime is in Phase 2.

Related

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing