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Cefaclor Capsules

Fundacion Clinic per a la Recerca Biomédica · FDA-approved active Small molecule

Cefaclor is a second-generation cephalosporin antibiotic that inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins.

Cefaclor is a second-generation cephalosporin antibiotic that inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins. Used for Bacterial infections including respiratory tract infections, urinary tract infections, skin and soft tissue infections, and otitis media.

At a glance

Generic nameCefaclor Capsules
SponsorFundacion Clinic per a la Recerca Biomédica
Drug classSecond-generation cephalosporin
TargetPenicillin-binding proteins (PBPs)
ModalitySmall molecule
Therapeutic areaInfectious Disease
PhaseFDA-approved

Mechanism of action

Cefaclor works by disrupting the cross-linking of peptidoglycan in the bacterial cell wall, leading to cell wall instability and bacterial death. It has a broader spectrum of activity than first-generation cephalosporins, particularly against gram-negative organisms and some anaerobes, while maintaining good gram-positive coverage.

Approved indications

Common side effects

Key clinical trials

Primary sources

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SourceUsed for
ClinicalTrials.govTrial enrolment, design, endpoints, results

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