Last reviewed · How we verify
CD70-targeting CAR-T cells
At a glance
| Generic name | CD70-targeting CAR-T cells |
|---|---|
| Sponsor | Chinese PLA General Hospital |
| Modality | Biologic |
| Phase | Phase 1 |
Approved indications
Common side effects
Key clinical trials
- A Phase I, Single-arm, Open-label Clinical Study to Evaluate the Safety, Pharmacokinetics, and Preliminary Efficacy of CHT101 Cell Infusion in Adult Subjects With Recurrent or Progressive Malignant Primary Brain Tumors（CROWN） (PHASE1)
- CD70.CAR for CD70+ Lymphoma, Myeloma and Solid Tumors (PHASE1)
- CAR BCMA-70 CAR-T Cells for the Treatment of High-risk Plasma Cell Neoplasms (EARLY_PHASE1)
- A Study to Investigate the Safety and Preliminary Efficacy of ALLO-329, an Allogeneic CAR T-cell Therapy, in Adults With Autoimmune Disease (PHASE1)
- Study of Ultra-Fast BCMA/CD70 CAR-T Therapy for Refractory SLE (PHASE1)
- Chimeric Antigen Receptor Treatment Targeting CD70 (SEVENTY) (PHASE1)
- CD70-Targeted CAR-T Therapy in CD70-Positive Advanced Solid Tumors (PHASE1)
- Safety and Efficacy of ALLO-316 in Subjects With Advanced or Metastatic Clear Cell Renal Cell Carcinoma (PHASE1)
Primary sources
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| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |