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BUTENAFINE HYDROCHLORIDE ›
Regulatory · United States
Marketing authorisations
FDA — authorised 17 October 2002
Application: NDA021408
Marketing authorisation holder: PHARMOBEDIENT
Local brand name: MENTAX-TC
Indication: CREAM — TOPICAL
Status: approved
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FDA — authorised 16 November 2017
Application: ANDA205181
Marketing authorisation holder: SUN PHARMA CANADA
Local brand name: BUTENAFINE HYDROCHLORIDE
Indication: CREAM — TOPICAL
Status: approved
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FDA
Safety signals — FAERS
Adverse reaction reports describe suspected side effects. A report does not mean the drug caused the event — co-medications, underlying disease and coincidence all contribute.
Window: 20 April 2025 – 20 April 2026
Total reports: 47
Most-reported reactions
Drug Ineffective — 16 reports (34.04%) Condition Aggravated — 5 reports (10.64%) Application Site Pain — 4 reports (8.51%) Aspartate Aminotransferase Increased — 4 reports (8.51%) Alanine Aminotransferase Increased — 3 reports (6.38%) Blood Creatinine Increased — 3 reports (6.38%) Cerebral Infarction — 3 reports (6.38%) Gait Disturbance — 3 reports (6.38%) Nausea — 3 reports (6.38%) Off Label Use — 3 reports (6.38%)
Source database →
BUTENAFINE HYDROCHLORIDE in other countries
Same drug, different regulators. Each page below lists the local marketing authorisation, HTA position, pricing, and adverse-event data.
Frequently asked questions
Is BUTENAFINE HYDROCHLORIDE approved in United States?
Yes. FDA authorised it on 17 October 2002; FDA authorised it on 16 November 2017; FDA has authorised it.
Who is the marketing authorisation holder for BUTENAFINE HYDROCHLORIDE in United States?
PHARMOBEDIENT holds the US marketing authorisation.