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bupropion and transdermal patch
Bupropion is a norepinephrine-dopamine reuptake inhibitor, which increases the levels of these neurotransmitters in the brain.
Bupropion is a norepinephrine-dopamine reuptake inhibitor, which increases the levels of these neurotransmitters in the brain. Used for Major depressive disorder, Smoking cessation.
At a glance
| Generic name | bupropion and transdermal patch |
|---|---|
| Sponsor | US Department of Veterans Affairs |
| Drug class | Norepinephrine-dopamine reuptake inhibitor |
| Target | Norepinephrine transporter, Dopamine transporter |
| Modality | Small molecule |
| Therapeutic area | Mental health, Smoking cessation |
| Phase | Phase 3 |
Mechanism of action
This action is thought to contribute to its antidepressant and smoking cessation effects. The transdermal patch formulation allows for a more consistent release of the drug into the bloodstream.
Approved indications
- Major depressive disorder
- Smoking cessation
Common side effects
- Headache
- Dry mouth
- Insomnia
- Nausea
- Dizziness
Key clinical trials
- Tobacco Treatment Optimization and Preferences During Concurrent Cancer Treatment (PHASE2)
- Embedding Comprehensive Smoking Cessation Programs Into Community Clinics (NA)
- Web-based Smoking Cessation Program for Tribal College Students (PHASE3)
- Mobile Contingency Management for Concurrent Abstinence From Alcohol and Smoking (PHASE4)
- Mobile Contingency Management for Marijuana and Tobacco Cessation (NA)
- Comparing Smoking Treatment Programs for Lighter Smokers - 1 (PHASE2)
- Tailored Tobacco Quitline for Rural Veterans (PHASE2)
- Treating Smokeless Tobacco Use in Rural Veterans (NA)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- bupropion and transdermal patch CI brief — competitive landscape report
- bupropion and transdermal patch updates RSS · CI watch RSS
- US Department of Veterans Affairs portfolio CI