Last reviewed · How we verify

BTV100 High dose

BioTheraVision, Inc. · Phase 2 active Small molecule

BTV100 is a monoclonal antibody targeting CD19.

BTV100 is a monoclonal antibody targeting CD19. Used for Relapsed or refractory B-cell non-Hodgkin lymphoma, Chronic lymphocytic leukemia.

At a glance

Generic nameBTV100 High dose
SponsorBioTheraVision, Inc.
Drug classCD19-targeting monoclonal antibody
TargetCD19
ModalitySmall molecule
Therapeutic areaOncology
PhasePhase 2

Mechanism of action

BTV100 works by binding to CD19 on the surface of B cells, marking them for destruction by the immune system. This leads to a reduction in B cell count and subsequent decrease in B cell-related diseases.

Approved indications

Common side effects

Key clinical trials

Primary sources

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SourceUsed for
ClinicalTrials.govTrial enrolment, design, endpoints, results

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