Last reviewed 2026-04-22 · How we verify

Bronchodilators inhalation

Bronchodilators relax airway smooth muscle to widen airways and improve airflow to the lungs.

Bronchodilators relax airway smooth muscle to widen airways and improve airflow to the lungs. Used for Asthma, Chronic obstructive pulmonary disease (COPD), Reversible airway obstruction.

At a glance

Mechanism of action

Bronchodilators work by stimulating beta-2 adrenergic receptors (beta-agonists) or blocking muscarinic receptors (anticholinergics) on airway smooth muscle, causing relaxation and bronchodilation. This reduces airway resistance and improves ventilation, making breathing easier for patients with obstructive airway diseases.

Approved indications

• Asthma
• Chronic obstructive pulmonary disease (COPD)
• Reversible airway obstruction

Common side effects

• Tremor
• Tachycardia
• Headache
• Nervousness
• Palpitations

Key clinical trials

• Nebulized or Inhaled Albuterol for Lymphangioleiomyomatosis (PHASE1, PHASE2)
• Safety and Efficacy of Inhaled BMD003 (CFTR mRNA) in Chinese Cystic Fibrosis Patients Aged ≥12 Years (EARLY_PHASE1)
• A 12-Week Treatment Study to Evaluate the Effectiveness of Albuterol Multidose Dry Powder Inhaler With Integrated Electronic Module Digital System (eMDPI DS) in Participants13 Years or Older With Asthma (PHASE4)
• Daratumumab in STK11 Mutated NSCLC (PHASE2)
• The Effect of NAC on Lung Function and CT Mucus Score (PHASE4)
• Impact of Inhaled PT003 on Complexity and Variability of Tidal Breathing and Oscillatory Mechanics in Stable COPD Patient (PHASE2)
• Effects of Inhaled Epinephrine on Systemic Allergic Reactions During Allergy Testing, Immunotherapy or Oral Challenges (PHASE1)
• Digital Physiotherapy for Pediatric Chronic Suppurative Lung Diseases (NA)

Primary sources

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