Last reviewed 2026-04-22 · How we verify

Bronchodilator Agents

Bronchodilator agents relax airway smooth muscle to increase airway diameter and improve airflow to the lungs.

Bronchodilator agents relax airway smooth muscle to increase airway diameter and improve airflow to the lungs. Used for Asthma, Chronic obstructive pulmonary disease (COPD), Reversible airway obstruction.

At a glance

Mechanism of action

Bronchodilators work through various mechanisms including beta-2 adrenergic receptor agonism, muscarinic receptor antagonism, or phosphodiesterase inhibition to reduce airway constriction. By relaxing the smooth muscle surrounding the airways, these agents decrease airway resistance and improve ventilation, making breathing easier for patients with obstructive airway diseases.

Approved indications

• Asthma
• Chronic obstructive pulmonary disease (COPD)
• Reversible airway obstruction

Common side effects

• Tremor
• Tachycardia
• Headache
• Nervousness
• Palpitations

Key clinical trials

• AI-Powered Sound Analysis for COPD Screening
• Nebulized or Inhaled Albuterol for Lymphangioleiomyomatosis (PHASE1, PHASE2)
• Predicting Risk Factors for Exacerbation of Chronic Obstructive Pulmonary Disease
• The Effect of NAC on Lung Function and CT Mucus Score (PHASE4)
• Impact of Multi-Component Interventions on High Risk COPD Population (NA)
• Impact of Inhaled PT003 on Complexity and Variability of Tidal Breathing and Oscillatory Mechanics in Stable COPD Patient (PHASE2)
• A Phase IIb Ensifentrine-glycopyrrolate Fixed-dose Combination Dose Ranging Study in Subjects With COPD (PHASE2)
• Assessing Role of Probiotics in Children Aged 6-36 Months Treated for Pneumonia (NA)

Primary sources

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