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BRN01
BRN01 is a small molecule targeting the CDK4/6 pathway.
BRN01 is a small molecule targeting the CDK4/6 pathway. Used for Breast cancer, HR-positive, HER2-negative.
At a glance
| Generic name | BRN01 |
|---|---|
| Sponsor | Centre Leon Berard |
| Drug class | CDK4/6 inhibitor |
| Target | CDK4/6 |
| Modality | Small molecule |
| Therapeutic area | Oncology |
| Phase | Phase 3 |
Mechanism of action
BRN01 works by inhibiting the CDK4/6 enzymes, which are involved in cell cycle progression. This inhibition leads to a decrease in cell proliferation and an increase in cell death, making it a potential therapeutic agent for various cancers.
Approved indications
- Breast cancer, HR-positive, HER2-negative
Common side effects
- Diarrhea
- Nausea
- Fatigue
Key clinical trials
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- BRN01 CI brief — competitive landscape report
- BRN01 updates RSS · CI watch RSS
- Centre Leon Berard portfolio CI