Last reviewed · How we verify

BreathID® Hp Lab System

Meridian Bioscience, Inc. · Phase 3 active Small molecule ✓ Verified Jun 2026

BreathID® Hp Lab System is a Small molecule drug developed by Meridian Bioscience, Inc.. It is currently in Phase 3 development for Detection of active Helicobacter pylori infection.

BreathID® Hp is a non-invasive diagnostic system that detects Helicobacter pylori infection by measuring labeled carbon dioxide in exhaled breath.

The BreathID Hp Lab System is a diagnostic tool used to detect Helicobacter Pylori infection. It is based on an oligonucleotide modality and is used in conjunction with a 13C-urea breath test.

Likelihood of approval
60.3% vs 58.3% industry baseline
If approved by FDA: likely 2028–2030
Steps remaining: NDA/BLA submission
Confidence: High
Why this estimate
  • Baseline phase 3 → approval rate +58.3pp
    Industry-wide phase 3 drugs reach approval ~58.3% of the time (BIO/Informa 2023 industry benchmark across all therapeutic areas).
  • Anti-infectives pathway favourability +2.0pp
    Microbiological endpoints + non-inferiority designs raise approval rates above baseline.
Predicted approval windows by jurisdiction (conditional on FDA approval)
Regulator Country Likely year Lag vs FDA
FDA US 2028–2030
EMA EU 2029–2031 +0.7 yr
MHRA GB 2029–2031 +0.7 yr
Health Canada CA 2029–2032 +0.9 yr
TGA AU 2029–2032 +1.2 yr
PMDA JP 2029–2032 +1.5 yr
NMPA CN 2030–2033 +2.3 yr
MFDS KR 2029–2032 +1.4 yr
CDSCO IN 2029–2033 +1.8 yr
ANVISA BR 2030–2033 +2.3 yr

Hover any row for the lag rationale. Lag estimates are reduced when the drug has FDA Breakthrough or EMA PRIME designation (sponsors file globally in parallel).

Estimate based on the BIO/Informa industry phase transition rates plus per-drug modifiers for therapeutic area, sponsor type, FDA designations, mechanism, and trial design. Per-jurisdiction lags from Tufts CSDD international approval studies. Not investment, clinical or regulatory advice. Methodology: /methodology#likelihood.

At a glance

Generic nameBreathID® Hp Lab System
SponsorMeridian Bioscience, Inc.
ModalitySmall molecule
Therapeutic areaGastroenterology / Infectious Disease
PhasePhase 3

Mechanism of action

The system uses the urea breath test (UBT) principle: patients ingest labeled urea (either 13C or 14C), which is metabolized by H. pylori urease enzyme into ammonia and labeled CO2. The labeled CO2 is absorbed into the bloodstream and exhaled in breath, where it is measured by the device to confirm active H. pylori infection. This provides a non-invasive alternative to endoscopic or serological testing.

Approved indications

Common side effects

No common side effects on file.

Key clinical trials

Primary sources

Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.

SourceUsed for
ClinicalTrials.govTrial enrolment, design, endpoints, results

Competitive intelligence

For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:

Frequently asked questions about BreathID® Hp Lab System

What is BreathID® Hp Lab System?

BreathID® Hp Lab System is a Small molecule drug developed by Meridian Bioscience, Inc., indicated for Detection of active Helicobacter pylori infection.

How does BreathID® Hp Lab System work?

BreathID® Hp is a non-invasive diagnostic system that detects Helicobacter pylori infection by measuring labeled carbon dioxide in exhaled breath.

What is BreathID® Hp Lab System used for?

BreathID® Hp Lab System is indicated for Detection of active Helicobacter pylori infection.

Who makes BreathID® Hp Lab System?

BreathID® Hp Lab System is developed by Meridian Bioscience, Inc. (see full Meridian Bioscience, Inc. pipeline at /company/meridian-bioscience-inc).

What development phase is BreathID® Hp Lab System in?

BreathID® Hp Lab System is in Phase 3.

Related

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing