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Botulinum toxin B
Botulinum toxin B is a Small molecule drug developed by United States Department of Defense. It is currently FDA-approved. Also known as: Myobloc.
Botulinum toxin B is a neurotoxic protein that prevents the release of the neurotransmitter acetylcholine from axon endings at the neuromuscular junction, causing flaccid paralysis. It has been studied as a potential treatment for various conditions, including Overactive Bladder, Urinary Urge Incontinence, and Dystonic Tremor Syndrome, among others.
At a glance
| Generic name | Botulinum toxin B |
|---|---|
| Also known as | Myobloc |
| Sponsor | United States Department of Defense |
| Modality | Small molecule |
| Phase | FDA-approved |
Approved indications
Common side effects
Key clinical trials
- A Clinical Trial to Evaluate Efficacy and Safety of Xeomin® Injections for Preventing Episodic Migraine (PHASE3)
- A Clinical Trial to Evaluate Efficacy and Safety of Xeomin® Injections for Preventing Chronic Migraine (PHASE3)
- A Study to Evaluate the Effectiveness and Safety of Dysport® for the Prevention of Episodic Migraine in Adults (PHASE3)
- A Study to Evaluate the Effectiveness and Safety of Dysport® for the Prevention of Chronic Migraine in Adults (PHASE3)
- Comparative Study Between Botulinum Toxin-A Injection and Shock Waves on Hypertrophic Scars in Hand-burned Children (NA)
- BT-011 Pharmacokinetics of Botulism Antitoxin Heptavalent in Pediatric Patients (PHASE4)
- Repeated Botulinum Toxin Type A Injections on Intramuscular Fat Accumulation in Individuals With Sleep Bruxism. (NA)
- A Study to Assess the Adverse Events of Intramuscular Injections of AGN-151586 and OnabotulinumtoxinA in Adult Participants for the Change of Glabellar Lines (GL) (PHASE1)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Botulinum toxin B CI brief — competitive landscape report
- Botulinum toxin B updates RSS · CI watch RSS
- United States Department of Defense portfolio CI
Frequently asked questions about Botulinum toxin B
What is Botulinum toxin B?
Who makes Botulinum toxin B?
Is Botulinum toxin B also known as anything else?
What development phase is Botulinum toxin B in?
Related
- Manufacturer: United States Department of Defense — full pipeline
- Also known as: Myobloc
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing