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Bone regeneration
Bone regeneration therapy stimulates osteogenic differentiation and new bone formation through biological or biomaterial-based approaches.
Bone regeneration therapy stimulates osteogenic differentiation and new bone formation through biological or biomaterial-based approaches. Used for Bone defects and fractures requiring regeneration.
At a glance
| Generic name | Bone regeneration |
|---|---|
| Also known as | Bio-Oss Collagen®, Bio-Gide® |
| Sponsor | São Paulo State University |
| Modality | Biologic |
| Therapeutic area | Orthopedics / Regenerative Medicine |
| Phase | FDA-approved |
Mechanism of action
This marketed product from São Paulo State University facilitates bone regeneration, likely through scaffolding materials, growth factor delivery, or stem cell-based strategies that promote osteoblast activity and mineralized matrix deposition. The exact mechanism depends on the specific formulation, which may involve biocompatible polymers, hydroxyapatite, or cellular components that create an environment conducive to bone healing and remodeling.
Approved indications
- Bone defects and fractures requiring regeneration
Common side effects
Key clinical trials
- Radiographic and Histological Assessment of GBR Using DBB Compared to Spontaneous Bone Regeneration of Maxillary Defects , Resulted From Enucleation of Intra-bony Cystic Lesions (NA)
- Reduced Time Interval for Implant Placement After Extraction Socket Preservation Using the Vega Plus Implants (NA)
- Evaluating The Use of CGF Made Plugs in Mandibular Extraction Sites of Lower Impacted 3rd Molars. (NA)
- Anti-HLA Antibodies After Bone Regeneration Surgery (NA)
- Narrow Implants Vs Standard Implants With Simultaneous GBR (NA)
- Collagenic vs Collagen-enriched Graft in Sinus Elevation: RCT (NA)
- Radiographical, Histomorphometrical and Biomarker Analysis After Maxillary Sinus Augmentation Utilizing Xenograft Particulate Bone Graft Mixed With Parathyroid Hormone (PHASE4)
- Performance and Safety of Lyoplant® in Guided Bone Regeneration (GBR) in Oral Surgery (NA)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Bone regeneration CI brief — competitive landscape report
- Bone regeneration updates RSS · CI watch RSS
- São Paulo State University portfolio CI