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Bioceramic putty
Bioceramic putty is a biocompatible ceramic-based material that fills and seals bone defects and root canals through direct contact and mechanical integration.
Bioceramic putty is a biocompatible ceramic-based material that fills and seals bone defects and root canals through direct contact and mechanical integration. Used for Root canal filling and obturation, Bone defect filling in dental and orthopedic applications, Periodontal defect management.
At a glance
| Generic name | Bioceramic putty |
|---|---|
| Sponsor | Mohamed Salah Elwakeel |
| Drug class | Biocompatible ceramic material / bone graft substitute |
| Modality | Small molecule |
| Therapeutic area | Dentistry / Orthopedics / Endodontics |
| Phase | FDA-approved |
Mechanism of action
Bioceramic putty consists of biocompatible ceramic particles suspended in a carrier medium, designed to be placed into bone cavities, root canals, or periodontal defects. The material sets through a hydration reaction and promotes bone regeneration and healing by providing a scaffold for new bone formation and creating a biocompatible seal that prevents bacterial contamination.
Approved indications
- Root canal filling and obturation
- Bone defect filling in dental and orthopedic applications
- Periodontal defect management
- Apical periodontitis treatment
Common side effects
- Minimal systemic toxicity
- Local inflammatory response (rare)
- Extrusion beyond apex (if overfilled)
Key clinical trials
- Epigallocatechin Gallate (EGCG) as a Flushing Agent During Full Pulpotomy in Mature Permanent Molars With Irreversible Pulpitis (NA)
- Vital Pulp Therapy vs. Root Canal Treatment in Mature Teeth With Irreversible Pulpitis (NA)
- A Comparison of Outcome of Pulpotomy on Immature Permanent Molars Between Different Calcium Silicate-based Materials : a 12 Months Clinical Study (NA)
- Bioceramic Putty Versus MTA in Pulpotomized Primary Teeth to be Covered With 3D Printed Resin Crowns Versus Stainless Steel Crown (NA)
- Evaluation Of Laser Versus Conventional Pulpotomies In Mature Molar Teeth With Irreversible Pulpitis (NA)
- Postoperative Pain After Pulpotomy in Children Using Calcium Silicate Cements With and Without Laser Therapy (NA)
- A Comparative Analysis of Biomaterials for Retrograde Filling in Apical Surgery. (NA)
- Evaluation of Guided Endodontic Microsurgery and Two Different Retrograde Filling Materials (NA)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Bioceramic putty CI brief — competitive landscape report
- Bioceramic putty updates RSS · CI watch RSS
- Mohamed Salah Elwakeel portfolio CI