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Bio-three
Bio-three is a probiotic formulation containing multiple beneficial bacterial strains that restore and maintain healthy gut microbiota.
Bio-three is a probiotic formulation containing multiple beneficial bacterial strains that restore and maintain healthy gut microbiota. Used for Diarrhea associated with antibiotic use, Irritable bowel syndrome, Digestive disorders and dysbiosis.
At a glance
| Generic name | Bio-three |
|---|---|
| Sponsor | Kaohsiung Veterans General Hospital. |
| Drug class | Probiotic |
| Modality | Small molecule |
| Therapeutic area | Gastroenterology |
| Phase | FDA-approved |
Mechanism of action
Bio-three works by introducing live beneficial bacteria (typically Clostridium butyricum, Bacillus mesentericus, and Enterococcus faecalis) into the gastrointestinal tract to restore normal intestinal flora balance. This helps improve digestive function, enhance intestinal barrier integrity, and support immune homeostasis through competitive exclusion of pathogenic organisms and production of short-chain fatty acids.
Approved indications
- Diarrhea associated with antibiotic use
- Irritable bowel syndrome
- Digestive disorders and dysbiosis
Common side effects
- Mild gastrointestinal discomfort
- Bloating
- Flatulence
Key clinical trials
- Development and Multicenter Validation of a Novel Bio-Anatomical Staging System for Predicting Survival and Tailoring Adjuvant Therapy in ESCC After Neoadjuvant Chemoimmunotherapy.
- An Open-Label Study of INV-1120 as a Single Agent and in Combination With Pembrolizumab in Adult Patients With Advanced Solid Tumors (PHASE1)
- A Prospective Registry for Patients at High-Risk for Pancreatic Cancer
- Pelvic Floor Shear-Wave Elastography in Healthy and Pudendal Neuralgia Women
- Novel Coding Strategies for Children With Cochlear Implants (NA)
- Apixaban VS Warfarin in AF Pts First Three Months After Repair or BIO AVR MVR (PHASE3)
- Rehabilitation With Biofeedback for People After Stroke (NA)
- Mechanisms of Pregnancy Vascular Adaptations
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Bio-three CI brief — competitive landscape report
- Bio-three updates RSS · CI watch RSS
- Kaohsiung Veterans General Hospital. portfolio CI