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BHV-8000
BHV-8000 is a calcitonin gene-related peptide receptor antagonist.
BHV-8000 is a calcitonin gene-related peptide receptor antagonist. Used for Migraine prevention.
At a glance
| Generic name | BHV-8000 |
|---|---|
| Sponsor | Biohaven Therapeutics Ltd. |
| Drug class | Calcitonin gene-related peptide receptor antagonist |
| Target | Calcitonin gene-related peptide receptor |
| Modality | Small molecule |
| Therapeutic area | Neurology |
| Phase | Phase 2 |
Mechanism of action
BHV-8000 works by blocking the action of calcitonin gene-related peptide (CGRP) at its receptor, which is involved in the transmission of pain signals. This mechanism is thought to be beneficial in the treatment of migraine and other headache disorders.
Approved indications
- Migraine prevention
Common side effects
- Dizziness
- Nausea
- Headache
Key clinical trials
- A Study to Determine if BHV-8000 is Effective, Safe and Tolerable as a Treatment for Adults Living With Early Parkinson's Disease (PHASE2, PHASE3)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- BHV-8000 CI brief — competitive landscape report
- BHV-8000 updates RSS · CI watch RSS
- Biohaven Therapeutics Ltd. portfolio CI