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benzydamine HCl

Benzydamine HCl is a nonsteroidal anti-inflammatory drug (NSAID) that acts as a cyclooxygenase (COX) inhibitor.

Benzydamine HCl is a nonsteroidal anti-inflammatory drug (NSAID) that acts as a cyclooxygenase (COX) inhibitor. Used for Oral mucositis.

At a glance

Mechanism of action

By inhibiting COX enzymes, benzydamine HCl reduces the production of prostaglandins, which are mediators of inflammation and pain. This results in anti-inflammatory and analgesic effects.

Approved indications

• Oral mucositis

Common side effects

• Gastrointestinal upset

Key clinical trials

• The Aim of This Study is to Compare the Effects of Two Different Topical Agents (KLOROBEN® and KLORHEX PLUS®) Used in the Surgical Extraction of Mandibular Bilateral Mesioangular Impacted Third Molars on Postoperative Pain, Edema, and Trismus. (NA)
• Benzydamine for Radiation-Induced Oral Mucositis in Patients Receiving High-Dose Radiotherapy (PHASE4)
• The Effect of Supplementary Foods Containing Trypsin, Chymotrypsin and Serratia Peptidase on Healing After Impacted Wisdom Tooth Surgery (NA)
• Palatability Study of Five Formulations of Benzydamine HCl Lozenges (PHASE1)
• N Acetylcystene in Treatment of Radiotherapy Induced Oral Mucositis in Oral Cancer Patients (NA)
• Study to Evaluate the Efficacy and Safety of Different Doses of Graminidin With Anesthetic, a Metered Dose Topical Spray, in the Treatment of Acute Infectious and Inflammatory Pharyngeal Diseases Compared With Drug Septolete Total, Lozenges (PHASE2)
• Benzydamine Hydrochloride and Post-operative Sore Throat (EARLY_PHASE1)
• Evaluation of the Efficacy of Aloe-Vera el Versus Bezydamine Hydrochloride in the Prevention of Radiation Induced Oral Mucositis A Randamized Controlled Clinical Trial (PHASE4)

Primary sources

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