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BENOXINATE HYDROCHLORIDE
At a glance
| Generic name | BENOXINATE HYDROCHLORIDE |
|---|---|
| Modality | Small molecule |
| Phase | FDA-approved |
| First approval | 1982 |
Approved indications
Common side effects
- conjunctival redness
- temporary stinging
- burning
- allergic contact dermatitis
- drying and fissuring of the fingertips
- iritis with descemetitis
- corneal filaments
- sloughing of large areas of necrotic epithelium
- gray, ground glass appearance
- acute, intense and diffuse epithelial keratitis
- hyper-allergic corneal reaction
Key clinical trials
- Efficacy and Safety of Chloroprocaine 3% Gel and Oxybuprocaine 0.4% Eye Drops Anesthesia in Pediatric Population (PHASE3)
- Identification of Cellular Biomarkers of Rare Eye Diseases in Adults (NA)
- Effect of Four Different Diagnostic Eye Drops on Tear Film Thickness (PHASE3)
- Study to Evaluate the Efficacy and Safety of Different Doses of Graminidin With Anesthetic, a Metered Dose Topical Spray, in the Treatment of Acute Infectious and Inflammatory Pharyngeal Diseases Compared With Drug Septolete Total, Lozenges (PHASE2)
- Safety, Tolerability, and Pharmacokinetic Profile of Grammidin With Anesthetic, a Metered Dose Topical Spray in Healthy Volunteers (PHASE1)
- The Role of Adjuvant Corneal Crosslinking in the Management of Infective Keratitis (EARLY_PHASE1)
- Effectiveness of Intravitreal Injection of Aflibercept 8 mg in Resistant Diabetic Macular Edema, Retinal Vein Occlusion and Myopic Choroidal Neovascularisation Patients (EARLY_PHASE1)
- Change in Ocular Perfusion After Intravitreal Anti-VEGF in Patients with Age-related Maculopathy or Diabetic Macula Edema
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| FDA label | Mechanism, indications, dosing, boxed warnings, drug interactions |
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- BENOXINATE HYDROCHLORIDE CI brief — competitive landscape report
- BENOXINATE HYDROCHLORIDE updates RSS · CI watch RSS