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Beclomethasone (Clenil)
Beclomethasone is a corticosteroid that suppresses inflammatory and immune responses by binding to glucocorticoid receptors in the lungs.
Beclomethasone is a corticosteroid that suppresses inflammatory and immune responses by binding to glucocorticoid receptors in the lungs. Used for Asthma maintenance therapy, Chronic obstructive pulmonary disease (COPD).
At a glance
| Generic name | Beclomethasone (Clenil) |
|---|---|
| Also known as | Clenil |
| Sponsor | University Medical Center Groningen |
| Drug class | Inhaled corticosteroid |
| Target | Glucocorticoid receptor |
| Modality | Small molecule |
| Therapeutic area | Respiratory |
| Phase | FDA-approved |
Mechanism of action
Beclomethasone reduces inflammation in the airways by inhibiting the production of inflammatory mediators and decreasing immune cell infiltration. It is administered as an inhaled aerosol, allowing direct delivery to the lungs while minimizing systemic exposure. This localized anti-inflammatory action makes it effective for controlling asthma and chronic obstructive pulmonary disease (COPD) symptoms.
Approved indications
- Asthma maintenance therapy
- Chronic obstructive pulmonary disease (COPD)
Common side effects
- Oropharyngeal candidiasis
- Tremor
- Headache
- Dysphonia
- Throat irritation
Key clinical trials
- Preschool Wheeze: Inflammation/Infection Guided Management (PHASE2)
- Beta Blocker Therapy in Moderate to Severe COPD (PHASE4)
- Efficacy and Tolerability of Beclomethasone Plus Salbutamol in HFA pMDI Fixed Combination vs Beclomethasone Plus Salbutamol in CFC pMDI Fixed Combination in a 12-week Treatment Period of Adult Patients With Uncontrolled Asthma (PHASE3)
- Pilot Pharmacokinetic Clenil Study With AeroChamber Plus™ or Volumatic™ Spacer Devices (PHASE2)
- Efficacy of CHF1535 Via NEXT DPI Versus pMDI and BDP DPI100µg on PeakExpiratoryFlow in Asthmatic Patients (PHASE3)
- Combined Glucocorticoid Adrenergic Therapy For Wheezy Preschool Children (PHASE4)
- Effects of QVAR in Smokers With Asthma (PHASE4)
- Recurrent Wheezing in Infants: Risk Factors and Prevention With Probiotics. (PHASE3)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Beclomethasone (Clenil) CI brief — competitive landscape report
- Beclomethasone (Clenil) updates RSS · CI watch RSS
- University Medical Center Groningen portfolio CI