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BCMA CAR-T cells
BCMA-targeting CAR-T cells
BCMA-targeting CAR-T cells Used for Multiple myeloma.
At a glance
| Generic name | BCMA CAR-T cells |
|---|---|
| Also known as | BCMA CAR-T cells injection |
| Sponsor | Chongqing Precision Biotech Co., Ltd |
| Drug class | CAR-T cell therapy |
| Target | BCMA |
| Modality | Biologic |
| Therapeutic area | Oncology |
| Phase | Phase 2 |
Mechanism of action
BCMA-targeting CAR-T cells are a type of immunotherapy that uses genetically modified T cells to recognize and kill cancer cells expressing BCMA.
Approved indications
- Multiple myeloma
Common side effects
- Cytokine release syndrome
- Neutropenia
- Anemia
Key clinical trials
- Descartes-08 for Patients With Systemic Lupus Erythematosus (PHASE2)
- A Study Comparing Anitocabtagene Autoleucel to Standard of Care Therapy in Participants With Relapsed/ Refractory Multiple Myeloma (PHASE3)
- Study of GC012F, CAR-T Therapy Targeting CD19 and BCMA in Chinese Participants With Relapsed or Refractory AL Amyloidosis (PHASE1)
- Cluster of Differentiation 19 (CD19)/B Cell Maturation Antigen (BCMA) Chimeric Antigen Receptor T-Cell (CAR-T) Therapy for Refractory Autoimmune Diseases (NA)
- Study of PD-1Ab21-BCMA CAR-T Therapy for Consolidation of Multiple Myelomawith Renal Dysfunction (PHASE2)
- A Phase 1b/2 Study of CAR T Cell Therapy Targeting CD19 and BCMA in Participants With Relapsed or Refractory AL Amyloidosis. (PHASE1, PHASE2)
- Recombinant Human IL-7 (NT-I7) in Relapsed/Refractory Multiple Myeloma Following BCMA CAR-T Therapy (Cilta-cel) (PHASE1)
- Clinical Study to Evaluate the Safety and Efficacy of CAR-T in the Treatment of Relapsed or Refractory Multiple Myeloma (NA)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- BCMA CAR-T cells CI brief — competitive landscape report
- BCMA CAR-T cells updates RSS · CI watch RSS
- Chongqing Precision Biotech Co., Ltd portfolio CI