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Bayesian Prediction Tacrolimus dosage

NURIA LLOBERAS BLANCH · FDA-approved active Small molecule

This is a Bayesian prediction tool for personalizing tacrolimus dosing based on individual patient pharmacokinetics, not a drug itself.

This is a Bayesian prediction tool for personalizing tacrolimus dosing based on individual patient pharmacokinetics, not a drug itself. Used for Optimization of tacrolimus dosing in transplant recipients and autoimmune disease patients.

At a glance

Generic nameBayesian Prediction Tacrolimus dosage
Also known asTacrolimus
SponsorNURIA LLOBERAS BLANCH
ModalitySmall molecule
Therapeutic areaImmunology
PhaseFDA-approved

Mechanism of action

Bayesian prediction models use population pharmacokinetic data and individual patient characteristics to forecast tacrolimus blood concentrations and optimize dosing. This computational approach aims to achieve therapeutic drug levels more rapidly and accurately than standard dosing, reducing the need for frequent therapeutic drug monitoring adjustments. The tool is applied to tacrolimus, a calcineurin inhibitor immunosuppressant.

Approved indications

Common side effects

No common side effects on file.

Key clinical trials

Primary sources

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SourceUsed for
ClinicalTrials.govTrial enrolment, design, endpoints, results

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