Last reviewed 2026-04-23 · How we verify

Autologous Conditioned Serum

Autologous Conditioned Serum is a treatment that uses a patient's own blood to stimulate healing and reduce inflammation.

Autologous Conditioned Serum is a treatment that uses a patient's own blood to stimulate healing and reduce inflammation. Used for Osteoarthritis, Rheumatoid Arthritis.

At a glance

Mechanism of action

The serum is collected from the patient's own blood, which is then used to stimulate the body's natural healing processes. This can help to reduce inflammation and promote tissue repair.

Approved indications

• Osteoarthritis
• Rheumatoid Arthritis

Common side effects

• Pain
• Swelling
• Infection

Key clinical trials

• Base Editing Hematopoietic Stem Cell and T Cell Gene Therapy for CD40L-HyperIgM Syndrome: Single Patient Study (PHASE1, PHASE2)
• Comparison of Platelet-rich Plasma and Activated Cytokine-rich Serum Injection Treatments in Patients With Knee Osteoarthritis. (KOA PRP ACS) (NA)
• Efficacy of Autologous Conditioned Serum in Temporomandibular Joint Disorder (NA)
• Addition of JSP191 (C-kit Antibody) to Nonmyeloablative Hematopoietic Cell Transplantation for Sickle Cell Disease and Beta-Thalassemia (PHASE1, PHASE2)
• Lenalidomide and Combination Chemotherapy (DA-EPOCH-R) in Treating Patients With MYC-Associated B-Cell Lymphomas (PHASE1, PHASE2)
• Anti-CD19 Chimeric Antigen Receptor T-Cell Immunotherapy for Leukemias (PHASE1, PHASE2)
• Stem Cell Transplantation in Crohn's Disease (PHASE1, PHASE2)
• GD2 CAR T Cells in Diffuse Intrinsic Pontine Gliomas (DIPG) & Spinal Diffuse Midline Glioma(DMG) (PHASE1)

Primary sources

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