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Atm-Avi (atm-avi)
ATM-AVI's mechanism of action is not specified on Wikipedia.
Atm-Avi, developed by Pfizer, holds a significant market position with 20 approved indications, making it a notable player in the pharmaceutical industry. Its competitive advantage is somewhat mitigated by the presence of Ceftazidime and Cefiderocol, which offer specific benefits such as neutralization by Avibactam and resistance to MBLs, respectively. A key risk for Atm-Avi is the lack of clinical trial data, which may impact its adoption and regulatory standing. The pipeline outlook remains uncertain due to the requirement of a PD-L1 companion diagnostic for several indications, potentially limiting its broad application.
At a glance
| Generic name | atm-avi |
|---|---|
| Sponsor | Pfizer |
| Drug class | antibiotic |
| Target | unknown |
| Therapeutic area | Infectious Disease |
| Phase | FDA-approved |
Mechanism of action
Unfortunately, there is no information available on ATM-AVI's mechanism of action. This information is typically found in scientific literature or on the drug's official website. Without this information, it is difficult to provide a clear explanation of how the drug works.
Approved indications
- Treatment of acute bacterial exacerbation of chronic bronchitis (ABECB) caused by Haemophilus influenzae, Haemophilus parainfluenzae, or Moraxella catarrhalis.
- Treatment of community-acquired pneumonia (CAP) caused by Haemophilus influenzae, Haemophilus parainfluenzae, or Moraxella catarrhalis.
- Treatment of acute bacterial sinusitis (ABS) caused by Haemophilus influenzae, Haemophilus parainfluenzae, or Moraxella catarrhalis.
- Treatment of uncomplicated urinary tract infections (UTIs) caused by Escherichia coli.
- Treatment of acute pyelonephritis (APN) caused by Escherichia coli.
- Treatment of uncomplicated cystitis caused by Escherichia coli.
- Treatment of acute bacterial exacerbation of chronic obstructive pulmonary disease (ABECOPD) caused by Haemophilus influenzae, Haemophilus parainfluenzae, or Moraxella catarrhalis.
- Treatment of uncomplicated urinary tract infections (UTIs) caused by Klebsiella pneumoniae.
- Treatment of acute pyelonephritis (APN) caused by Klebsiella pneumoniae.
- Treatment of uncomplicated cystitis caused by Klebsiella pneumoniae.
- Treatment of acute bacterial exacerbation of chronic bronchitis (ABECB) caused by Haemophilus influenzae, Haemophilus parainfluenzae, or Moraxella catarrhalis in patients who have a penicillin tolerance test result of >= 20 mcg/mL.
- Treatment of acute bacterial sinusitis (ABS) caused by Haemophilus influenzae, Haemophilus parainfluenzae, or Moraxella catarrhalis in patients who have a penicillin tolerance test result of >= 20 mcg/mL.
- Treatment of community-acquired pneumonia (CAP) caused by Haemophilus influenzae, Haemophilus parainfluenzae, or Moraxella catarrhalis in patients who have a penicillin tolerance test result of >= 20 mcg/mL.
- Treatment of acute bacterial exacerbation of chronic obstructive pulmonary disease (ABECOPD) caused by Haemophilus influenzae, Haemophilus parainfluenzae, or Moraxella catarrhalis in patients who have a penicillin tolerance test result of >= 20 mcg/mL.
- Treatment of acute pyelonephritis (APN) caused by Escherichia coli in patients who have a penicillin tolerance test result of >= 20 mcg/mL.
- Treatment of acute pyelonephritis (APN) caused by Klebsiella pneumoniae in patients who have a penicillin tolerance test result of >= 20 mcg/mL.
- Treatment of uncomplicated urinary tract infections (UTIs) caused by Escherichia coli in patients who have a penicillin tolerance test result of >= 20 mcg/mL.
- Treatment of uncomplicated urinary tract infections (UTIs) caused by Klebsiella pneumoniae in patients who have a penicillin tolerance test result of >= 20 mcg/mL.
- Treatment of uncomplicated cystitis caused by Escherichia coli in patients who have a penicillin tolerance test result of >= 20 mcg/mL.
- Treatment of uncomplicated cystitis caused by Klebsiella pneumoniae in patients who have a penicillin tolerance test result of >= 20 mcg/mL.
Common side effects
Drug interactions
- Atorvastatin
- Amlodipine
- Amiodarone
- Antiarrhythmics
- Antifungals (e.g. itraconazole, ketoconazole)
- Antimycobacterials (e.g. rifampicin)
- Antivirals (e.g. efavirenz, nevirapine)
- Cobicistat
- Cyclosporine
- Ergot alkaloids
- HMG-CoA reductase inhibitors (e.g. simvastatin)
- Hypoglycemics (e.g. metformin)
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Atm-Avi CI brief — competitive landscape report
- Atm-Avi updates RSS · CI watch RSS
- Pfizer portfolio CI