Last reviewed · How we verify
ASC
ASC is an autologous stem cell therapy that promotes tissue regeneration and repair through the patient's own stem cells.
ASC is an autologous stem cell therapy that promotes tissue regeneration and repair through the differentiation and engraftment of patient-derived stem cells. Used for Cartilage defects and osteoarthritis, Soft tissue injuries.
At a glance
| Generic name | ASC |
|---|---|
| Also known as | (Autologous Adipose-derived Mesenchymal Stem Cells) |
| Sponsor | Anterogen Co., Ltd. |
| Drug class | Autologous stem cell therapy |
| Modality | Biologic |
| Therapeutic area | Regenerative Medicine |
| Phase | FDA-approved |
Mechanism of action
ASC (Autologous Stem Cell) harnesses the patient's own adipose-derived stem cells to stimulate healing and reduce inflammation in damaged tissues. The cells are isolated, expanded ex vivo, and reintroduced to the target site where they differentiate and secrete bioactive factors that promote angiogenesis, reduce fibrosis, and modulate immune responses.
Approved indications
- Osteoarthritis (knee)
- Cartilage defects
Common side effects
- Injection site pain or swelling
- Temporary increase in inflammation
- Infection at harvest or injection site
Key clinical trials
- Evaluation of Allogenic Mesenchymal Stem Cell (MSC) Injection Therapy for Refractory Graft-versus-Host Disease (GVHD) Unresponsive to Conventional Treatments (PHASE2)
- Asciminib & Standard-of-Care Integration in Maintenance Therapy for POST Allogeneic Stem Cell Transplant (Allo-HSCT) of Patient With Ph+ B-ALL or Blastic Transformed CML (PHASE2)
- Active Surveillance Cultures for Multidrug Resistant Gram-Negative Organisms at an Acute Care Hospital
- Clinical Trial on Bowel Preparation Comparing Mannitol 100g to Plenvu Both in a Same Day Regimen (CLEARWAY) (PHASE3)
- TVB-2640 and Trastuzumab With Paclitaxel or Endocrine Therapy for Treatment of HER2 Positive Metastatic Breast Cancer (PHASE2)
- Safety and Psychological Effects of Psilocybin and D-Serine Formulation in Healthy Volunteers (PHASE1)
- Investigating the Efficacy of Autologous, Adipose-derived Mesenchymal Stem Cell Therapy for the Treatment of Sexual Function Impairment in Women Aged 40-50 (PHASE1, PHASE2)
- Cervical Cancer Screening of Postmenopausal Women in Low- and Middle-income Countries Using HPV Self-sampling and Triage by Genotyping and Cytology
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |