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Aquasol A
Aquasol A is a water-miscible formulation of vitamin A (retinol) that provides systemic vitamin A supplementation for deficiency states.
Aquasol A is a water-miscible formulation of vitamin A (retinol) that provides systemic vitamin A supplementation for deficiency states. Used for Vitamin A deficiency, Malabsorption syndromes requiring vitamin A supplementation, Xerophthalmia prevention and treatment.
At a glance
| Generic name | Aquasol A |
|---|---|
| Also known as | vitamin A |
| Sponsor | Glasgow Royal Infirmary |
| Drug class | Vitamin A supplement |
| Target | Retinoid receptors (RAR, RXR) |
| Modality | Small molecule |
| Therapeutic area | Nutritional deficiency / Ophthalmology |
| Phase | FDA-approved |
Mechanism of action
Vitamin A is an essential fat-soluble vitamin that plays critical roles in vision, immune function, and cellular differentiation. Aquasol A's water-soluble formulation allows for better absorption and bioavailability compared to oil-based vitamin A preparations, making it suitable for patients with malabsorption disorders or those requiring parenteral or oral supplementation.
Approved indications
- Vitamin A deficiency
- Malabsorption syndromes requiring vitamin A supplementation
- Xerophthalmia prevention and treatment
Common side effects
- Hypervitaminosis A (with chronic overdose)
- Nausea
- Headache
- Skin irritation (at injection site if parenteral)
Key clinical trials
- Dinutuximab With Chemotherapy, Surgery and Stem Cell Transplantation for the Treatment of Children With Newly Diagnosed High Risk Neuroblastoma (PHASE3)
- Lenalidomide and Dinutuximab With or Without Isotretinoin in Treating Younger Patients With Refractory or Recurrent Neuroblastoma (PHASE1)
- Virtual Reality and Computerized Cognitive Intervention for Mild Cognitive Impairment in Heart Failure (NA)
- Effect of the Consumption of Cookies Enriched With Plant Proteins and of a Vitamin D Supplement on the Progression of Sarcopenia in the Elderly (NA)
- Pilot Trial of Supplemental Vitamin A and Nicotinamide (EARLY_PHASE1)
- Combination of Oral and Topical Whitening Agents for Reducing Skin Pigmentation (NA)
- Child Health, Agriculture and Integrated Nutrition (NA)
- Microbiome and Health Indicators in People With Obesity, Prediabetes and Type 2 Diabetes Undergoing a Lifestyle Intervention (NA)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Aquasol A CI brief — competitive landscape report
- Aquasol A updates RSS · CI watch RSS
- Glasgow Royal Infirmary portfolio CI