Last reviewed · How we verify
Eliquis — drug interactions
Apixaban selectively inhibits Factor Xa, decreasing thrombin generation and thrombus development.
Drug interactions
- Combined P-gp and strong CYP3A4 inhibitors (e.g., ketoconazole, itraconazole, ritonavir)
- Clarithromycin
- Combined P-gp and strong CYP3A4 inducers (e.g., rifampin, carbamazepine, phenytoin, St. John's wort)
- Antiplatelet agents, fibrinolytics, heparin, aspirin, chronic NSAID use
Contraindications
- Active pathological bleeding
- Severe hypersensitivity reaction to apixaban (e.g., anaphylactic reactions)
See also
- Full profile: Eliquis
- Side effects: /side-effects
- Dosage & administration: /dosage
- Mechanism of action: /mechanism
- Cost & pricing: /cost
- Clinical trials: /clinical-trials
- Patents & exclusivity: /patents
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing