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antiseptic bundle
An antiseptic bundle combines multiple antimicrobial agents and protocols to reduce surgical site infections and healthcare-associated infections through comprehensive skin and environmental decontamination.
An antiseptic bundle combines multiple antimicrobial agents and protocols to reduce surgical site infections and healthcare-associated infections through comprehensive skin and environmental decontamination. Used for Surgical site infection prevention, Healthcare-associated infection prevention.
At a glance
| Generic name | antiseptic bundle |
|---|---|
| Also known as | Medications applied at home by patient for 5 days. |
| Sponsor | University of Minnesota |
| Drug class | Antiseptic/infection prevention bundle |
| Modality | Small molecule |
| Therapeutic area | Infection Prevention / Perioperative Care |
| Phase | FDA-approved |
Mechanism of action
The bundle typically includes antiseptic skin preparation, chlorhexidine or iodine-based solutions, and standardized infection prevention protocols applied perioperatively or in clinical settings. By using multiple complementary antimicrobial approaches simultaneously, the bundle achieves broader spectrum coverage and reduces pathogen survival on skin and surgical sites, thereby lowering infection rates compared to single-agent approaches.
Approved indications
- Surgical site infection prevention
- Healthcare-associated infection prevention
Common side effects
- Skin irritation or contact dermatitis
- Allergic reaction (iodine or chlorhexidine sensitivity)
Key clinical trials
- Effectiveness of Screening and Decolonization of S. Aureus to Prevent S. Aureus Surgical Site Infections in Surgery Outpatients
- The Effect of Bundle Application on Surgical Site Infection (NA)
- Polihexanide SSIs Measures Bundle (PSMB) During Enhanced Recovery After Major Digestive Surgery (PHASE4)
- Evaluation of the Introduction of a Colorectal Bundle in Left Sided Colorectal Resections (NA)
- Ultrasound Guided Block for Postoperative Analgesia in Arthroscopic Shoulder Surgery (NA)
- Immediate Stiffness Changes in Myofascial Trigger Points After Dry Needling (NA)
- Topical Antisepsis in Head and Neck Cancer Surgery
- S. Aureus Screening and Decolonization (PHASE4)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- antiseptic bundle CI brief — competitive landscape report
- antiseptic bundle updates RSS · CI watch RSS
- University of Minnesota portfolio CI