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Antipsychotic treatment
Antipsychotic treatment works by modulating dopamine and/or serotonin neurotransmission in the brain to reduce psychotic symptoms.
Antipsychotic treatment works by modulating dopamine and/or serotonin neurotransmission in the brain to reduce psychotic symptoms. Used for Schizophrenia, Bipolar disorder, Psychotic disorders.
At a glance
| Generic name | Antipsychotic treatment |
|---|---|
| Also known as | Antipsychotic drugs |
| Sponsor | Fundación Pública Andaluza Progreso y Salud |
| Drug class | Antipsychotic |
| Modality | Small molecule |
| Therapeutic area | Psychiatry/Neurology |
| Phase | Phase 3 |
Mechanism of action
Antipsychotics typically block dopamine D2 receptors and/or serotonin 5-HT2A receptors, reducing hyperactivity in mesolimbic and mesocortical pathways associated with psychosis. This mechanism helps alleviate positive symptoms such as hallucinations and delusions, and some agents also improve negative symptoms and cognitive dysfunction.
Approved indications
- Schizophrenia
- Bipolar disorder
- Psychotic disorders
Common side effects
- Extrapyramidal symptoms (EPS)
- Weight gain
- Metabolic syndrome
- Hyperprolactinemia
- Sedation
- Orthostatic hypotension
Key clinical trials
- Incentives and Long-Acting Injectable Adherence After Involuntary Hospitalization (NA)
- Immune Mechanisms of Antipsychotic Treatment Response
- Cue-based Intervention in Prospective Memory and Medication Adherence. (NA)
- Cerebellum-based Imaging Neural Markers for Antipsychotic Response
- Psychiatric Multi-omics and Neuroimaging Project
- Cognitive Impairment Characteristics and Biological Mechanisms in Untreated Severe Mental Illness
- Medication Adherence in Severe Mental Illness: a Promotion Program (NA)
- Pharmacist-led Interventions in Psychiatric Patients (NA)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Antipsychotic treatment CI brief — competitive landscape report
- Antipsychotic treatment updates RSS · CI watch RSS
- Fundación Pública Andaluza Progreso y Salud portfolio CI