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Antibiotics administration
Antibiotics kill or inhibit bacterial pathogens by targeting bacterial cell wall synthesis, protein synthesis, or DNA replication.
Antibiotics kill or inhibit bacterial pathogens by targeting bacterial cell wall synthesis, protein synthesis, or DNA replication. Used for Bacterial infections in gynecologic oncology patients, Prophylaxis of infection in immunocompromised cancer patients.
At a glance
| Generic name | Antibiotics administration |
|---|---|
| Sponsor | The Central and Eastern European Gynecologic Oncology Group |
| Drug class | Antibiotic (broad class) |
| Modality | Small molecule |
| Therapeutic area | Infectious Disease / Supportive Care in Oncology |
| Phase | FDA-approved |
Mechanism of action
Antibiotics are a broad class of antimicrobial agents used to treat bacterial infections. Different antibiotic classes work through distinct mechanisms: beta-lactams inhibit cell wall synthesis, aminoglycosides and macrolides disrupt protein synthesis, and fluoroquinolones interfere with DNA replication. In gynecologic oncology contexts, antibiotics are typically used as supportive care to prevent or treat infections in immunocompromised cancer patients.
Approved indications
- Bacterial infections in gynecologic oncology patients
- Prophylaxis of infection in immunocompromised cancer patients
Common side effects
- Gastrointestinal disturbance (nausea, diarrhea)
- Allergic reactions
- Photosensitivity (fluoroquinolones)
- Ototoxicity (aminoglycosides)
Key clinical trials
- Learning Process of Fourth Year Medical Students During a Doctor-patient Relationship Training
- Comparison of Two Dosage Adjustment Strategies of Vancomycin in Children (NA)
- Comparison of Oral Antibiotics For Bone Infections of the Leg and Foot (PHASE4)
- Durability of Three Monthly Loading Doses With Faricimab in Treatment-naïve Neovascular Age-related Macular Degeneration
- Individualized Precision Isavuconazole Therapy Guided by PK/PD Principles for the Geriatric Population
- Intracalvariosseous Plus Intravenous Antibiotics for Moderate-to-Severe Bacterial Meningitis (NA)
- Real-World Efficacy and Safety Analysis of Omadacycline for the Treatment of Diabetic Foot Infections and Acute Osteomyelitis
- A Study of Doxycycline to Treat Chlamydial Infection (PHASE4)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
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