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Anti-inflammatory drugs
Anti-inflammatory drugs reduce inflammation by inhibiting inflammatory pathways and mediators in the body.
At a glance
| Generic name | Anti-inflammatory drugs |
|---|---|
| Sponsor | Genentech, Inc. |
| Modality | Small molecule |
| Therapeutic area | Immunology |
| Phase | Phase 3 |
Mechanism of action
Anti-inflammatory drugs work through various mechanisms depending on the specific agent, commonly by inhibiting cyclooxygenase (COX) enzymes, suppressing cytokine production, or modulating immune cell activity. Genentech's anti-inflammatory candidates in Phase 3 typically employ biologic mechanisms such as monoclonal antibodies targeting specific inflammatory cytokines or their receptors. These approaches aim to reduce excessive immune activation while preserving beneficial immune function.
Approved indications
Common side effects
Key clinical trials
- A Study to Evaluate the Long-term Safety, Tolerability, and Efficacy of Subcutaneous Sonelokimab in Participants With Psoriatic Arthritis (PHASE3)
- A Study to Understand How the Study Medicine Dazukibart Works in People With Idiopathic Inflammatory Myopathies (PHASE3)
- Evaluation of High Dose Prednisolone Pharmacokinetics in the Acute and Chronic Setting
- Phase I/II Study of Pacritinib, A JAK2/IRAK1/CSF1R Inhibitor, in Refractory Chronic Graft-Versus-Host Disease (cGVHD) After Allogeneic Hematopoietic Stem Cell Transplantation (HSCT) (PHASE1, PHASE2)
- In-Bedroom Renewed Air as Anti-inflammatory Adjuvant Therapy in Cancer Survivors (NA)
- Anti-Inflammatory Effects of Pecan Nut Oil Supplementation in Adults With Overweight: A Randomized Controlled Parallel-Group Clinical Trial (NA)
- PBMC as Biomarkers of Diabetic Cardiomyopathy
- Efficacy of Chemically Distinct Nonsteroidal Anti-Inflammatory Drugs (NSAIDs) and Pain Phenotypes in Adhesive Capsulitis (NA)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Anti-inflammatory drugs CI brief — competitive landscape report
- Anti-inflammatory drugs updates RSS · CI watch RSS
- Genentech, Inc. portfolio CI