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Anlotinib
Anlotinib is a Small molecule drug developed by Tianjin Medical University Cancer Institute and Hospital. It is currently FDA-approved. Also known as: Anlotinib Hydrochloride Capsules, Focusv, almonertinib, AL3818.
Anlotinib, also known as catequentinib, is a vascular endothelial growth factor receptor 2 inhibitor that belongs to the class of small molecule inhibitors. It is used to treat various types of cancer, including locally advanced or metastatic non-small cell lung cancer, advanced soft-tissue sarcoma, and other conditions such as uterine cervical neoplasms and platinum-resistant recurrent clear cell ovarian cancer.
At a glance
| Generic name | Anlotinib |
|---|---|
| Also known as | Anlotinib Hydrochloride Capsules, Focusv, almonertinib, AL3818, Anlotinib Hydrochloride |
| Sponsor | Tianjin Medical University Cancer Institute and Hospital |
| Modality | Small molecule |
| Therapeutic area | Other |
| Phase | FDA-approved |
Approved indications
Common side effects
Key clinical trials
- Benmelstobart in Combination With Anlotinib and Oral Metronomic Cyclophosphamide in the Treatment of Recurrent Epithelial OvariaN, Fallopian Tube, or Primary Peritoneal Cancer (PHASE2)
- SBRT Plus Anlotinib and Bimepolizumab in Locally Advanced or Metastatic Renal Cell Carcinoma (PHASE2)
- Carboplatin/Cisplatin + Etoposide + Benmelstobart Sequential Benmelstobart Combined With Anlotinib Versus Carboplatin/Cisplatin + Etoposide + Tislelizumab Sequential Tislelizumab in the Treatment of Extensive Stage Small Cell Lung Cancer (PHASE2)
- Chidamide in Combination With Toripalimab and Anlotinib in Recurrent/Metastatic Nasopharyngeal Carcinoma. (PHASE1, PHASE2)
- A Study of Bemosubaiabimab Combined With Anlotinib and Radiotherapy and Chemotherapy for the Treatment of Oligometastatic Esophageal Cancer (PHASE2)
- Liposomal Irinotecan, Vincristine, Temozolomide, and Anlotinib for R/R Pediatric Solid Tumors (PHASE2)
- A Phase III Study of First-line Anlotinib Combined With Benmelstobart in Patients With Advanced Esophageal Squamous Cell Carcinoma (PHASE3)
- Anlotinib Plus Whole-Brain Radiotherapy for Brain Metastases in SCLC Patients. (PHASE3)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Anlotinib CI brief — competitive landscape report
- Anlotinib updates RSS · CI watch RSS
- Tianjin Medical University Cancer Institute and Hospital portfolio CI
Frequently asked questions about Anlotinib
What is Anlotinib?
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What development phase is Anlotinib in?
Related
- Manufacturer: Tianjin Medical University Cancer Institute and Hospital — full pipeline
- Therapeutic area: All drugs in Other
- Also known as: Anlotinib Hydrochloride Capsules, Focusv, almonertinib, AL3818, Anlotinib Hydrochloride
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing