Last reviewed · How we verify
Anesthetic spray
Anesthetic spray is a Small molecule drug developed by Tufts University. It is currently in Phase 1 development.
Anesthetic spray, specifically lidocaine spray, is used to provide topical anesthesia and relieve pain in various conditions, including oral mucositis and superior laryngeal nerve block. The spray form of lidocaine is a small molecule that acts as a mu opioid receptor agonist, providing easy application and better patient acceptance compared to other forms of lidocaine administration.
-
Baseline phase 1 → approval rate
+9.6pp
Industry-wide phase 1 drugs reach approval ~9.6% of the time (BIO/Informa 2023 industry benchmark across all therapeutic areas).
| Regulator | Country | Likely year | Lag vs FDA |
|---|---|---|---|
| FDA | US | 2033–2036 | — |
| EMA | EU | 2034–2037 | +0.7 yr |
| MHRA | GB | 2034–2037 | +0.7 yr |
| Health Canada | CA | 2034–2038 | +0.9 yr |
| TGA | AU | 2034–2038 | +1.2 yr |
| PMDA | JP | 2034–2038 | +1.5 yr |
| NMPA | CN | 2035–2039 | +2.3 yr |
| MFDS | KR | 2034–2038 | +1.4 yr |
| CDSCO | IN | 2034–2039 | +1.8 yr |
| ANVISA | BR | 2035–2039 | +2.3 yr |
Hover any row for the lag rationale. Lag estimates are reduced when the drug has FDA Breakthrough or EMA PRIME designation (sponsors file globally in parallel).
Estimate based on the BIO/Informa industry phase transition rates plus per-drug modifiers for therapeutic area, sponsor type, FDA designations, mechanism, and trial design. Per-jurisdiction lags from Tufts CSDD international approval studies. Not investment, clinical or regulatory advice. Methodology: /methodology#likelihood.
At a glance
| Generic name | Anesthetic spray |
|---|---|
| Sponsor | Tufts University |
| Modality | Small molecule |
| Phase | Phase 1 |
Approved indications
Common side effects
Key clinical trials
- This Clinical Trial Aims to Compare the Effectiveness of Two Intra-pulpal Cryotherapy Techniques-Endo-ice and Ice Sticks-in Decreasing Intra-operative Pain and Enhancing the Success of Local Anesthesia During Pulpectomy of Mandibular Molars With Symptomatic Irreversible Pulpitis. (NA)
- Cryotherapy as a Topical Anesthetic in Healthy Children (PHASE4)
- Ultrasound-guided Thyroid Cartilage Plane Block for Awake Intubation (NA)
- Pain Perception During Intra-Articular Knee Joint Injection: What is the Effect of Needle Gauge and the Use of Ethyl Chloride? (PHASE4)
- The Effects of Preoperative Intranasal Administration of Dexmedetomidine and Esketamine on Negative Postoperative Behavioral Changes in Children With Autism Spectrum Disorder (NA)
- Understanding Host-pathogen Interaction in the Respiratory Mucosa During Pregnancy
- Does Ethyl Chloride Spray Work? (NA)
- Pain and Anxiety in Pediatric Dentistry: Computer-Controlled vs. Traditional Anesthesia (NA)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Anesthetic spray CI brief — competitive landscape report
- Anesthetic spray updates RSS · CI watch RSS
- Tufts University portfolio CI
Frequently asked questions about Anesthetic spray
What is Anesthetic spray?
Who makes Anesthetic spray?
What development phase is Anesthetic spray in?
Related
- Manufacturer: Tufts University — full pipeline
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing