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Anesthesia induction
Anesthesia induction refers to the initiation phase of general anesthesia, typically using intravenous agents to rapidly induce unconsciousness and loss of protective airway reflexes.
Anesthesia induction refers to the initiation phase of general anesthesia, typically using intravenous agents to rapidly induce unconsciousness and loss of protective airway reflexes. Used for Induction of general anesthesia for surgical procedures, Rapid sequence intubation in emergency settings.
At a glance
| Generic name | Anesthesia induction |
|---|---|
| Sponsor | Second Affiliated Hospital of Xi'an Jiaotong University |
| Modality | Small molecule |
| Therapeutic area | Anesthesiology |
| Phase | FDA-approved |
Mechanism of action
Anesthesia induction is a procedural approach rather than a single drug entity. It commonly employs intravenous agents such as propofol, thiopental, or etomidate that act on central nervous system receptors (primarily GABA receptors) to produce rapid onset of unconsciousness. The choice of agent depends on patient factors, surgical requirements, and institutional protocols.
Approved indications
- Induction of general anesthesia for surgical procedures
- Rapid sequence intubation in emergency settings
Common side effects
- Hypotension
- Respiratory depression
- Bradycardia
- Injection site pain
- Apnea
Key clinical trials
- Effect of Lidocaine Infusion Versus Dexmedemidine Infusion on the Neurocognitive Function of Elderly Patients Undergoing Endoscopic Retrograde Cholangiopancreatography(ERCP): a Randomized, Controlled Trial. (NA)
- Effect of Scalp Block on Intraoperative Hemodynamics and Postoperative Pain in Craniotomy Patients" (NA)
- Induction of Labor by Cervical Ripening and Transcutaneous Electrical Nerve Stimulation (TENS) (NA)
- The Relationship Between Opioid-Free Anesthesia and Postoperative Agitation-Delirium and Quality of Recovery in Pediatric Ear, Nose, and Throat Cases Monitored With Perioperative Bispectral Index
- Educational Cartoon to Reduce Preoperative Anxiety in Children (CALM-KIDS) (NA)
- Ultrasound Assessment of Femoral Vein and Inferior Vena Cava Collapsibility to Predict Spinal Anesthesia-Induced Hypotension
- Impact of Sugammadex Versus Neostigmine on Early Postoperative Pulmonary Function (NA)
- Methadone Pharmacokinetics in Cardiac Surgery (PHASE4)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Anesthesia induction CI brief — competitive landscape report
- Anesthesia induction updates RSS · CI watch RSS
- Second Affiliated Hospital of Xi'an Jiaotong University portfolio CI