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Anagliptin BID Treatment
Anagliptin BID Treatment is a DPP-4 inhibitor Small molecule drug developed by JW Pharmaceutical. It is currently FDA-approved for Type 2 diabetes mellitus. Also known as: Sitagliptin QD Treatment.
Anagliptin inhibits dipeptidyl peptidase-4 (DPP-4), prolonging the action of incretin hormones to increase insulin secretion and reduce glucagon in response to meals.
Anagliptin inhibits dipeptidyl peptidase-4 (DPP-4), prolonging the action of incretin hormones to increase insulin secretion and reduce glucagon in response to meals. Used for Type 2 diabetes mellitus.
At a glance
| Generic name | Anagliptin BID Treatment |
|---|---|
| Also known as | Sitagliptin QD Treatment |
| Sponsor | JW Pharmaceutical |
| Drug class | DPP-4 inhibitor |
| Target | Dipeptidyl peptidase-4 (DPP-4) |
| Modality | Small molecule |
| Therapeutic area | Diabetes |
| Phase | FDA-approved |
Mechanism of action
As a DPP-4 inhibitor, anagliptin prevents the degradation of GLP-1 and GIP, incretin hormones that regulate postprandial glucose levels. By extending the half-life of these hormones, anagliptin enhances glucose-dependent insulin secretion and suppresses glucagon release, thereby lowering blood glucose in patients with type 2 diabetes. The BID (twice-daily) dosing regimen optimizes glycemic control throughout the day.
Approved indications
- Type 2 diabetes mellitus
Common side effects
- Nasopharyngitis
- Headache
- Hypoglycemia
- Upper respiratory tract infection
Key clinical trials
- Glycemic Variability of Combination Therapies in T2DM (PHASE4)
- MAGE of Anagliptin Compared With Sitagliptin With Type 2 Diabetes Mellitus (PHASE4)
- Efficacy and Safety of CWP-0403 Compared to Sitagliptin in Patients With Type 2 Diabetes Mellitus Insufficiently Controlled With Metformin Alone (PHASE3)
- A Study to Efficacy and Safety of CWP-0403 in Type 2 Diabetes Mellitus Patients (PHASE3)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Anagliptin BID Treatment CI brief — competitive landscape report
- Anagliptin BID Treatment updates RSS · CI watch RSS
- JW Pharmaceutical portfolio CI
Frequently asked questions about Anagliptin BID Treatment
What is Anagliptin BID Treatment?
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Related
- Drug class: All DPP-4 inhibitor drugs
- Target: All drugs targeting Dipeptidyl peptidase-4 (DPP-4)
- Manufacturer: JW Pharmaceutical — full pipeline
- Therapeutic area: All drugs in Diabetes
- Indication: Drugs for Type 2 diabetes mellitus
- Also known as: Sitagliptin QD Treatment