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Aloe Vera
Aloe vera contains polysaccharides and bioactive compounds that promote wound healing, reduce inflammation, and stimulate tissue repair through moisturization and antimicrobial activity.
Aloe vera contains polysaccharides and bioactive compounds that promote wound healing, reduce inflammation, and stimulate tissue repair through moisturization and antimicrobial activity. Used for Wound healing and tissue repair, Oral mucositis and gum health, Minor burns and skin irritation.
At a glance
| Generic name | Aloe Vera |
|---|---|
| Also known as | AV, green, Aloe Vera Gel (LIFEPLAN) |
| Sponsor | Government Dental College and Research Institute, Bangalore |
| Drug class | Botanical/Natural product |
| Modality | Small molecule |
| Therapeutic area | Dermatology |
| Phase | FDA-approved |
Mechanism of action
Aloe vera gel contains acemannan and other polysaccharides that enhance fibroblast proliferation and collagen synthesis, promoting epithelialization. Its compounds exhibit anti-inflammatory properties by inhibiting prostaglandin and leukotriene synthesis, and demonstrate antimicrobial activity against various bacteria and fungi. These combined effects accelerate wound closure and tissue regeneration.
Approved indications
- Wound healing and tissue repair
- Oral mucositis and gum health
- Minor burns and skin irritation
Common side effects
- Contact dermatitis
- Skin irritation
- Allergic reaction
Key clinical trials
- Study of TRE Seals on Early Post-operative Subjects (NA)
- Temporary Inactivation of Strong Muscle Sensation to Improve Rehabilitation Interventions in SCI (PHASE1)
- Improving Postoperative Recovery: A Study of Multimodal Perineal Analgesia Protocol (MPAP) After Vaginal Surgery (PHASE4)
- Evaluation of Performance and Safety of Carbopol 980 NF 0.2%- Based Medical Device in the Management of Patients With Glaucomar or Ocular Hypertension and Concomitant Dry Eye Syndrome on Multiple Long-term Topical Hypotensive Therapy (NA)
- Antibacterial Mouthwash for Pharyngeal Gonorrhea Prevention (PHASE2)
- Research on the Evolution, Geometry, and Alterations of the Periorbital Region Based on Age and Deformations (NA)
- Aldena STAR Particles (NA)
- Comparing of Sesame Oil, Nitroglycerin Ointment, and Aloe Vera Gel (PHASE2)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |