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AlloDerm
AlloDerm is a processed human cadaveric dermal allograft that provides a scaffold for tissue regeneration and wound healing.
AlloDerm is a processed human cadaveric dermal allograft that provides a scaffold for tissue regeneration and wound healing. Used for Soft tissue augmentation and reconstruction, Burn wound coverage, Chronic wound healing.
At a glance
| Generic name | AlloDerm |
|---|---|
| Also known as | donated allograft human dermis, regenerative tissue matrix, AlloDerm SELECT™ RTM,biohorizons |
| Sponsor | Stephen E. Feinberg |
| Drug class | Acellular dermal matrix allograft |
| Modality | Biologic |
| Therapeutic area | Regenerative Medicine / Wound Care |
| Phase | FDA-approved |
Mechanism of action
AlloDerm is an acellular dermal matrix derived from donated human skin that has been processed to remove cellular components while preserving the extracellular matrix structure. When placed in a wound or surgical site, it serves as a biological scaffold that promotes neovascularization, fibroblast infiltration, and integration with host tissue, facilitating natural tissue regeneration and repair.
Approved indications
- Soft tissue augmentation and reconstruction
- Burn wound coverage
- Chronic wound healing
- Periodontal and oral surgical applications
- Cosmetic and reconstructive surgery
Common side effects
- Infection
- Graft rejection or failure to integrate
- Seroma or hematoma formation
- Allergic reaction
Key clinical trials
- Safety and Feasibility of Robotic SP Nipple Sparing Mastectomy (NA)
- Root Coverage Using ADM and Coronally Positioned Tunnel With or Without Enamel Matrix Derivative (PHASE4)
- Alveolar Ridge Preservation With Putty Allograft vs. Putty Alloplast Graft (PHASE4)
- The Use of Alloderm Versus Dermacell in Immediate Implant Based Breast Reconstruction (NA)
- Microderm for Root Coverage Procedures (PHASE4)
- PUBMIC (Prophylactic Use of Biologic Mesh in Ileal Conduit) (NA)
- Keratinized Tissue Augmentation Using Porcine Collagen Matrix (Mucoderm®) Around Dental Implant (PHASE1)
- BREAST ADM Trial for Alloplastic Breast Reconstruction (NA)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |