Last reviewed · How we verify
Alkaline Phosphatase
Alkaline Phosphatase is an enzyme that breaks down phosphate-containing compounds.
Alkaline Phosphatase is an enzyme that breaks down phosphate-containing compounds. Used for Treatment of hypophosphatasia.
At a glance
| Generic name | Alkaline Phosphatase |
|---|---|
| Also known as | AP, BIAP, CIAP |
| Sponsor | AM-Pharma |
| Modality | Small molecule |
| Therapeutic area | Oncology |
| Phase | Phase 2 |
Mechanism of action
It plays a crucial role in bone mineralization and liver function. Alkaline Phosphatase deficiency can lead to conditions such as rickets or osteomalacia.
Approved indications
- Treatment of hypophosphatasia
Common side effects
- Hypersensitivity reactions
Key clinical trials
- Fecal Microbiota Transplantation for Primary Sclerosing Cholangitis - Randomized Study Versus Sham Transplantation (PHASE2)
- Phase 3 Study of ALXN1850 Versus Placebo in Adolescent and Adult Participants With HPP Who Have Not Previously Been Treated With Asfotase Alfa (PHASE3)
- A Study of Elafibranor in Adults With Primary Biliary Cholangitis and Inadequate Response or Intolerance to Ursodeoxycholic Acid. (PHASE3)
- Evaluation of Serum TRACP-5b, BALP, and 25-Hydroxyvitamin D3 Levels in Stage III Periodontitis Patients (NA)
- Study of Saroglitazar Magnesium for PBC Patients With Incomplete Response or Intolerant to UDCA Therapy (PHASE3)
- Comparing UDCA and Corticosteroids in Immunotherapy Induced Cholestatic Hepatitis (PHASE2)
- Targeted Protein Fortification in Extremely Low Birth Weight Preterm Infants (NA)
- Anti-ALPP CAR-T Cells Immunotherapy for Advanced Solid Tumors (PHASE1, PHASE2)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Alkaline Phosphatase CI brief — competitive landscape report
- Alkaline Phosphatase updates RSS · CI watch RSS
- AM-Pharma portfolio CI