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alcoholic chlorhexidine
Chlorhexidine in alcoholic solution acts as a broad-spectrum antimicrobial agent that disrupts bacterial cell membranes and denatures proteins.
Chlorhexidine in alcoholic solution acts as a broad-spectrum antimicrobial agent that disrupts bacterial cell membranes and denatures proteins. Used for Skin antisepsis and disinfection, Wound cleansing and preparation, Preoperative skin preparation.
At a glance
| Generic name | alcoholic chlorhexidine |
|---|---|
| Also known as | ChloraPrep 2% |
| Sponsor | Centre Hospitalier Universitaire de Saint Etienne |
| Drug class | Antiseptic/Disinfectant |
| Modality | Small molecule |
| Therapeutic area | Infection Prevention/Dermatology |
| Phase | FDA-approved |
Mechanism of action
Chlorhexidine is a biguanide antiseptic that binds to and disrupts the cell membranes of bacteria, fungi, and some viruses, leading to leakage of cellular contents and cell death. The alcoholic formulation enhances penetration and provides rapid antimicrobial activity. It is commonly used as a topical antiseptic for skin and wound disinfection.
Approved indications
- Skin antisepsis and disinfection
- Wound cleansing and preparation
- Preoperative skin preparation
Common side effects
- Skin irritation or sensitization
- Contact dermatitis
- Allergic reaction
Key clinical trials
- Intrathecal MoRphine Versus Transabdominal Plane Block (TAP) Block for AnalGesic Management in Elective Caesarean Section (PHASE4)
- Pyrocarbon Interposition Arthroplasty of the Elbow (NA)
- Comparison of Alcoholic Chlorhexidine 2% Versus Alcoholic Povidone Iodine for Infections Prevention With Cardiac Resynchronization Therapy Device Implantation (PHASE4)
- Comparing Minimally Invasive Treatments for Pilonidal Disease: LA POPA Trial (Laser And Pit-picking OR Pit-picking Alone) (NA)
- ROSSINI 2 - Reduction of Surgical Site Infection Using Several Novel Interventions (PHASE3)
- Comparison of the Effectiveness of Ultrasound-guided Versus Radioguided Medial Lumbar Bundle Branch Block (NA)
- Salivary SARS-CoV-2 Load of Covid-19 Patients After Oral Antimicrobial Solutions and Dentifrices (NA)
- PVP Iodine vs Chlorhexidine in Alcohol for Disinfection of the Surgical Site (PHASE4)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- alcoholic chlorhexidine CI brief — competitive landscape report
- alcoholic chlorhexidine updates RSS · CI watch RSS
- Centre Hospitalier Universitaire de Saint Etienne portfolio CI