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Acthar ›
Regulatory · United States
Marketing authorisations
FDA — authorised 29 April 1952
Application: NDA008372
Marketing authorisation holder: MALLINCKRODT IRELAND
Local brand name: ACTHAR GEL
Indication: INJECTABLE — INJECTION
Status: approved
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FDA
Safety signals — FAERS
Adverse reaction reports describe suspected side effects. A report does not mean the drug caused the event — co-medications, underlying disease and coincidence all contribute.
Window: 20 April 2025 – 20 April 2026
Total reports: 2,064
Most-reported reactions
Drug Ineffective — 276 reports (13.37%) Fatigue — 252 reports (12.21%) Death — 225 reports (10.9%) Multiple Sclerosis Relapse — 218 reports (10.56%) Weight Increased — 206 reports (9.98%) Headache — 188 reports (9.11%) Condition Aggravated — 179 reports (8.67%) Dyspnoea — 178 reports (8.62%) Insomnia — 175 reports (8.48%) Asthenia — 167 reports (8.09%)
Source database →
Acthar in other countries
Same drug, different regulators. Each page below lists the local marketing authorisation, HTA position, pricing, and adverse-event data.
Other Other approved in United States
Frequently asked questions
Is Acthar approved in United States?
Yes. FDA authorised it on 29 April 1952; FDA has authorised it.
Who is the marketing authorisation holder for Acthar in United States?
MALLINCKRODT IRELAND holds the US marketing authorisation.