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ACT guided Routine Treatment
ACT guided Routine Treatment is a clinical management strategy that uses Artemisinin-based Combination Therapy (ACT) with routine diagnostic testing to optimize malaria treatment outcomes.
ACT guided Routine Treatment is a treatment strategy that uses Artemisinin-based Combination Therapy (ACT) guided by diagnostic testing to optimize malaria treatment outcomes. Used for Malaria (uncomplicated and severe forms, guided by diagnostic confirmation).
At a glance
| Generic name | ACT guided Routine Treatment |
|---|---|
| Sponsor | GlaxoSmithKline |
| Modality | Small molecule |
| Therapeutic area | Infectious Disease |
| Phase | FDA-approved |
Mechanism of action
This is a treatment protocol rather than a single drug entity, combining artemisinin-based antimalarial combinations with systematic diagnostic guidance to ensure appropriate patient selection and dosing. The approach aims to improve treatment efficacy, reduce drug resistance, and minimize unnecessary antimalarial use through evidence-based routine testing protocols.
Approved indications
- Malaria (uncomplicated and severe forms)
Common side effects
- Nausea
- Vomiting
- Abdominal pain
- Headache
- Fever
Key clinical trials
- The Impact of Fast Antimicrobial Sensitivity Testing Tools on Stewardship Antibiotic and Clinical Outcome (ACT-FAST) (NA)
- Rehabilitation Program for Bladder Control in Individuals With Incomplete Spinal Cord Injury (NA)
- FAB Programme for Parents of Children With NDD (NA)
- SIB-Time Web-application Tool for Typically Developing Siblings (NA)
- Family Nurture Intervention in the NICU at The Valley Hospital (NA)
- Asthma Control Test Guided Treatment in Chinese Subjects (PHASE4)
- Texting for Relapse Prevention (NA)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- ACT guided Routine Treatment CI brief — competitive landscape report
- ACT guided Routine Treatment updates RSS · CI watch RSS
- GlaxoSmithKline portfolio CI