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Methadyl (acetylmethadol)
Methadyl (generic name: acetylmethadol) is a drug. It is currently in unknown development for Opioid dependence.
Methadyl works by blocking potassium channels in the brain to stabilize neuronal activity and reduce withdrawal symptoms.
Methadyl, also known as acetylmethadol, is a synthetic opioid analgesic that is a racemic mixture of alphacetylmethadol and betacetylmethadol. It is a small molecule used in the treatment of opioid and cocaine abuse, often in combination with contingency management procedures and behavioral therapy.
At a glance
| Generic name | acetylmethadol |
|---|---|
| Target | Mu-type opioid receptor |
| Therapeutic area | Neuroscience |
| Phase | unknown |
Mechanism of action
Imagine your brain is like a city with many busy streets. When you're addicted to opioids, those streets get really chaotic and hard to navigate. Methadyl helps calm down the streets by blocking the flow of potassium ions, which helps reduce the chaos and makes it easier to manage withdrawal symptoms.
Approved indications
- Opioid dependence
Common side effects
Key clinical trials
- LAAM-HAART PET Imaging (EARLY_PHASE1)
- Feasibility Study of Take-Home LAAM Medication - 3 (PHASE4)
- The Efficacy of Methadyl Acetate (LAAM) and Contingency Management Procedures for Treating Dual Opioid and Cocaine Abuse - 1 (PHASE2)
- Evaluation of L-alpha-acetylmethadol (LAAM) in Methadone Patients - 5 (PHASE2)
- Treatment of Opioid/Heroin Dependence: Comparison of Three Medication Dosing Regimens (PHASE2)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Methadyl CI brief — competitive landscape report
- Methadyl updates RSS · CI watch RSS
- portfolio CI
Frequently asked questions about Methadyl
What is Methadyl?
How does Methadyl work?
What is Methadyl used for?
What is the generic name of Methadyl?
What development phase is Methadyl in?
What does Methadyl target?
Related
- Target: All drugs targeting Mu-type opioid receptor
- Manufacturer: — full pipeline
- Therapeutic area: All drugs in Neuroscience
- Indication: Drugs for Opioid dependence
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing