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Hydrocortisone And Acetic Acid (ACETIC ACID)
Hydrocortisone and Acetic Acid, originally developed by HI TECH PHARMA and currently owned by Hikma, is a small molecule acetic acid drug class targeting Tyrosine-protein kinase Lck. It was FDA approved in 1960 for the treatment of otitis externa. The drug is off-patent with 7 generic manufacturers, indicating it is commercially available as a generic product. Key safety considerations include the potential for local skin irritation and allergic reactions. This medication works by reducing inflammation and infection in the affected ear.
At a glance
| Generic name | ACETIC ACID |
|---|---|
| Sponsor | Hikma |
| Drug class | acetic acid |
| Target | Tyrosine-protein kinase Lck |
| Modality | Small molecule |
| Therapeutic area | Immunology |
| Phase | FDA-approved |
| First approval | 1960 |
Approved indications
- Superficial external auditory canal infections
Common side effects
- local irritation
- stinging
- burning
Key clinical trials
- A Vaccine (CMV-MVA Triplex Vaccine) for the Enhancement of CMV-Specific Immunity and the Prevention of CMV Viremia in Patients Undergoing Haploidentical Hematopoietic Stem Cell Transplant (PHASE1)
- Testing the Addition of an Anti-cancer Drug, Navtemadlin, to the Usual Treatments (Cytarabine and Idarubicin) in Patients With Acute Myeloid Leukemia (PHASE1)
- Testing a New Chemotherapy Drug, KRT-232 (AMG-232) in Combination With Decitabine and Venetoclax in Patients With Acute Myeloid Leukemia (PHASE1)
- Efficacy of Chemically Distinct Nonsteroidal Anti-Inflammatory Drugs (NSAIDs) and Pain Phenotypes in Adhesive Capsulitis (NA)
- Effect of an Intervention With Apple Cider Vinegar on Glycemic Variability and Lipid Profile in Patients With Type 2 Diabetes Mellitus (NA)
- Demineralized Dentin Allograft Versus Demineralized Dentin Autograft for Socket Preservation (NA)
- A Clinical Trial to Investigate the Efficacy of Bragg Apple Cider Vinegar on Blood Glucose Control in a Healthy Adult Population (NA)
- Clinic vs Clinic+Community Outreach HPV Self-Collection to Increase Cervical Screening in Women With HIV (NA)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| FDA label | Mechanism, indications, dosing, boxed warnings, drug interactions |
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Hydrocortisone And Acetic Acid CI brief — competitive landscape report
- Hydrocortisone And Acetic Acid updates RSS · CI watch RSS
- Hikma portfolio CI