Last reviewed · How we verify
Acetadote
At a glance
| Generic name | Acetadote |
|---|---|
| Also known as | acetylcysteine |
| Sponsor | University of Texas Southwestern Medical Center |
| Target | Cystine/glutamate transporter, Cytochrome c, Glutathione synthetase |
| Modality | Small molecule |
| Therapeutic area | Respiratory |
| Phase | FDA-approved |
Approved indications
- Amyloidosis
- Atelectasis due to Mucous Obstruction
- Bronchiectasis
- Bronchitis
- Contrast Media-Induced Nephrotoxicity Prevention
- Cystic fibrosis of the lung
- General anesthesia
- Poisoning by acetaminophen
- Support of pincer nail correction
- Thick Bronchial Secretions
Common side effects
- Rash
- Urticaria/Facial flushing
- Pruritus
- Hypersensitivity reactions
- Gastrointestinal disorders
- Nausea
- Cardiac disorders
- Tachycardia
Serious adverse events
- Fatal anaphylaxis
- Fluid overload
- Hypersensitivity reactions (severe)
Key clinical trials
- Effects of NAC on Symptoms of CHR Patients (NA)
- Individualized Multiplex Pathophysiological Treatment of Severe Acute Infections: N-Acetylcysteine (PHASE4)
- Glutathione in Mild Cognitive Impairment (EARLY_PHASE1)
- A Study to Explore if Long-term Use of Mucinex Can Help With Symptoms in Patients With Stable Chronic Bronchitis. (PHASE4)
- Prospective Treatment Efficacy in IPF Using Genotype for Nac Selection (PRECISIONS) Trial (PHASE3)
- N-Acetylcysteine for Smoking Cessation in Tobacco and Cannabis Co-Use (PHASE4)
- A Clinical Trial Via Telepsychiatry of Treatments for the Management of Emotional Dysregulation in Youth (PHASE4)
- Comparative Clinical Study to Evaluate the Possible Efficacy and Safety of Oral N-Acetyl Cysteine Versus Rectal Diclofenac in the Prevention of Post Endoscopic Retrograde Cholangiopancreatography Pancreatitis (PHASE1, PHASE2)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Acetadote CI brief — competitive landscape report
- Acetadote updates RSS · CI watch RSS
- University of Texas Southwestern Medical Center portfolio CI