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ACEI/DIU
ACEI/DIU is a combination drug that inhibits angiotensin-converting enzyme while providing diuretic activity to reduce blood pressure.
ACEI/DIU is a combination drug that inhibits angiotensin-converting enzyme (ACE) while providing diuretic activity to reduce blood pressure and fluid retention. Used for Hypertension, Heart failure.
At a glance
| Generic name | ACEI/DIU |
|---|---|
| Sponsor | Shanghai Jiao Tong University School of Medicine |
| Drug class | ACE inhibitor/Diuretic combination |
| Target | Angiotensin-converting enzyme (ACE) |
| Modality | Small molecule |
| Therapeutic area | Cardiovascular |
| Phase | FDA-approved |
Mechanism of action
ACE inhibitors block the conversion of angiotensin I to angiotensin II, reducing vasoconstriction and aldosterone secretion. The diuretic component enhances sodium and water excretion, further lowering blood pressure. Together, these mechanisms reduce cardiac workload and improve blood pressure control in hypertensive patients.
Approved indications
- Hypertension
Common side effects
- Cough
- Dizziness
- Hyperkalemia
- Hypotension
- Electrolyte imbalance
Key clinical trials
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- ACEI/DIU CI brief — competitive landscape report
- ACEI/DIU updates RSS · CI watch RSS
- Shanghai Jiao Tong University School of Medicine portfolio CI