Last reviewed · How we verify
ABI injection
ABI injection is used to treat atrial fibrillation by ablating the heart tissue causing the arrhythmia.
ABI injection is used to treat atrial fibrillation by ablating the heart tissue causing the arrhythmia. Used for Atrial fibrillation for stroke prevention, Atrial fibrillation for symptomatic control.
At a glance
| Generic name | ABI injection |
|---|---|
| Sponsor | Istanbul Training and Research Hospital |
| Drug class | Cardiac ablation agent |
| Modality | Biologic |
| Therapeutic area | Cardiovascular |
| Phase | Phase 3 |
Mechanism of action
The procedure involves using radiofrequency energy to destroy the abnormal electrical pathways in the heart, restoring a normal heart rhythm. This is achieved through the injection of a solution that helps to visualize the heart tissue during the ablation process.
Approved indications
- Atrial fibrillation for stroke prevention
- Atrial fibrillation for symptomatic control
Common side effects
- Cardiac tamponade
- Pneumothorax
- Pericardial effusion
- Stroke
- Death
Key clinical trials
- Testing the Addition of the Pill Chemotherapy, Cabozantinib, to the Standard Immune Therapy Nivolumab Compared to Standard Chemotherapy for Non-small Cell Lung Cancer (PHASE2)
- CompassHER2-pCR: Decreasing Chemotherapy for Breast Cancer Patients After Pre-surgery Chemo and Targeted Therapy (PHASE2)
- Effects of Recombinant Human Growth Hormone in Elderly Patients With Moderate to Severe Acute Brain Injury (GH-ABI-RCT) (PHASE4)
- Difluoromethylornithine and High Dose Testosterone With Enzalutamide in Metastatic Castration-Resistant Prostate Cancer (PHASE2)
- Recombinant EphB4-HSA Fusion Protein With Standard Chemotherapy Regimens in Treating Patients With Advanced or Metastatic Solid Tumors (PHASE1)
- Radium-223 Dichloride and Abiraterone Acetate Compared to Placebo and Abiraterone Acetate for Men With Cancer of the Prostate When Medical or Surgical Castration Does Not Work and When the Cancer Has Spread to the Bone, Has Not Been Treated With Chemotherapy and is Causing no or Only Mild Symptoms (PHASE3)
- SMMART Adaptive Clinical Treatment (ACT) Trial (EARLY_PHASE1)
- A Study Evaluating Treatment Regimens Containing Vebicorvir (ABI-H0731) in Participants With Chronic Hepatitis B Infection (PHASE2)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- ABI injection CI brief — competitive landscape report
- ABI injection updates RSS · CI watch RSS
- Istanbul Training and Research Hospital portfolio CI