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Abb-R-CHOP
Abb-R-CHOP is a combination chemotherapy regimen that targets rapidly dividing cancer cells.
Abb-R-CHOP is a combination chemotherapy regimen that targets rapidly dividing cancer cells. Used for Non-Hodgkin lymphoma.
At a glance
| Generic name | Abb-R-CHOP |
|---|---|
| Sponsor | Asan Medical Center |
| Drug class | Chemotherapy regimen |
| Target | CD20 |
| Modality | Small molecule |
| Therapeutic area | Oncology |
| Phase | Phase 2 |
Mechanism of action
It combines the anti-CD20 monoclonal antibody rituximab with the chemotherapy agents cyclophosphamide, doxorubicin, vincristine, and prednisone. This combination works by inducing cell death in rapidly dividing cancer cells, such as those found in non-Hodgkin lymphoma.
Approved indications
- Non-Hodgkin lymphoma
Common side effects
- Neutropenia
- Thrombocytopenia
- Anemia
- Infection
- Fatigue
Key clinical trials
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |