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Abb-R-CHOP

Asan Medical Center · Phase 2 active Small molecule

Abb-R-CHOP is a combination chemotherapy regimen that targets rapidly dividing cancer cells.

Abb-R-CHOP is a combination chemotherapy regimen that targets rapidly dividing cancer cells. Used for Non-Hodgkin lymphoma.

At a glance

Generic nameAbb-R-CHOP
SponsorAsan Medical Center
Drug classChemotherapy regimen
TargetCD20
ModalitySmall molecule
Therapeutic areaOncology
PhasePhase 2

Mechanism of action

It combines the anti-CD20 monoclonal antibody rituximab with the chemotherapy agents cyclophosphamide, doxorubicin, vincristine, and prednisone. This combination works by inducing cell death in rapidly dividing cancer cells, such as those found in non-Hodgkin lymphoma.

Approved indications

Common side effects

Key clinical trials

Primary sources

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SourceUsed for
ClinicalTrials.govTrial enrolment, design, endpoints, results