Last reviewed 2026-05-31 · How we verify

Mercaptobenzothiazole (2-mercaptobenzothiazole)

FDA-approved active ✓ Verified May 2026 Quality 10/100

Mercaptobenzothiazole (generic name: 2-mercaptobenzothiazole) is a Standardized Chemical Allergen drug. It is currently FDA-approved.

Mercaptobenzothiazole is a small molecule organosulfur compound with the formula C6H4(NH)SC=S, used as a reagent in organic synthesis and for the sulfur vulcanization of rubber. It is also used in the form of a copper nickel titanium arch wire in orthodontic treatment, specifically in the I-arch System, during the alignment stage.

At a glance

Generic name	2-mercaptobenzothiazole
Drug class	Standardized Chemical Allergen
Target	Proteasome subunit beta type-8
Therapeutic area	Immunology
Phase	FDA-approved

Approved indications

No approved indications tracked.

Common side effects

No common side effects on file.

Key clinical trials

Clinical Performance of the I-arch System During the Initial Stage of Orthodontic Treatment (NA)

Primary sources

Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.

Source	Used for
ClinicalTrials.gov	Trial enrolment, design, endpoints, results

Competitive intelligence

For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:

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Frequently asked questions about Mercaptobenzothiazole

What is Mercaptobenzothiazole?

Mercaptobenzothiazole (2-mercaptobenzothiazole) is a Standardized Chemical Allergen drug.

What is the generic name of Mercaptobenzothiazole?

2-mercaptobenzothiazole is the generic (nonproprietary) name of Mercaptobenzothiazole.

What drug class is Mercaptobenzothiazole in?

Mercaptobenzothiazole belongs to the Standardized Chemical Allergen class. See all Standardized Chemical Allergen drugs at /class/standardized-chemical-allergen.

What development phase is Mercaptobenzothiazole in?

Mercaptobenzothiazole is FDA-approved (marketed).

What does Mercaptobenzothiazole target?

Mercaptobenzothiazole targets Proteasome subunit beta type-8 and is a Standardized Chemical Allergen.

Drug class: All Standardized Chemical Allergen drugs
Target: All drugs targeting Proteasome subunit beta type-8
Manufacturer: — full pipeline
Therapeutic area: All drugs in Immunology

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing