Last reviewed 2026-05-27 · How we verify

10E7 NTCD spores

Leiden University Medical Center · Phase 1 active Biologic ✓ Verified May 2026 Quality 0/100

10E7 NTCD spores is a Biologic drug developed by Leiden University Medical Center. It is currently in Phase 1 development.

Here's a 2-sentence factual summary of 10E7 NTCD spores based on the provided facts: 10E7 NTCD spores were used as an intervention in a clinical trial (NCT05693077) studying the colonization of healthy volunteers with Clostridioides difficile. The mechanism and modality of 10E7 NTCD spores are currently unknown, as per the information available on ChEMBL.

Likelihood of approval

9.6% vs 9.6% industry baseline

If approved by FDA: likely 2033–2036

Steps remaining: Phase 2 → Phase 3 → NDA/BLA submission

Confidence: Medium

Why this estimate

Baseline phase 1 → approval rate +9.6pp
Industry-wide phase 1 drugs reach approval ~9.6% of the time (BIO/Informa 2023 industry benchmark across all therapeutic areas).

Predicted approval windows by jurisdiction (conditional on FDA approval)

Regulator	Country	Likely year	Lag vs FDA
FDA	US	2033–2036	—
EMA	EU	2034–2037	+0.7 yr
MHRA	GB	2034–2037	+0.7 yr
Health Canada	CA	2034–2038	+0.9 yr
TGA	AU	2034–2038	+1.2 yr
PMDA	JP	2034–2038	+1.5 yr
NMPA	CN	2035–2039	+2.3 yr
MFDS	KR	2034–2038	+1.4 yr
CDSCO	IN	2034–2039	+1.8 yr
ANVISA	BR	2035–2039	+2.3 yr

Hover any row for the lag rationale. Lag estimates are reduced when the drug has FDA Breakthrough or EMA PRIME designation (sponsors file globally in parallel).

Estimate based on the BIO/Informa industry phase transition rates plus per-drug modifiers for therapeutic area, sponsor type, FDA designations, mechanism, and trial design. Per-jurisdiction lags from Tufts CSDD international approval studies. Not investment, clinical or regulatory advice. Methodology: /methodology#likelihood.

At a glance

Generic name	10E7 NTCD spores
Sponsor	Leiden University Medical Center
Modality	Biologic
Phase	Phase 1

Approved indications

No approved indications tracked.

Common side effects

No common side effects on file.

Key clinical trials

Clostridioides Difficile Colonisation (PHASE1)

Primary sources

Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.

Source	Used for
ClinicalTrials.gov	Trial enrolment, design, endpoints, results

Competitive intelligence

For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:

10E7 NTCD spores CI brief — competitive landscape report
10E7 NTCD spores updates RSS · CI watch RSS
Leiden University Medical Center portfolio CI

Frequently asked questions about 10E7 NTCD spores

What is 10E7 NTCD spores?

10E7 NTCD spores is a Biologic drug developed by Leiden University Medical Center.

Who makes 10E7 NTCD spores?

10E7 NTCD spores is developed by Leiden University Medical Center (see full Leiden University Medical Center pipeline at /company/leiden-university-medical-center).

What development phase is 10E7 NTCD spores in?

10E7 NTCD spores is in Phase 1.

Manufacturer: Leiden University Medical Center — full pipeline

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing