Last reviewed 2026-04-20 · How we verify

1 ampoule of Hylan GF-20

University of Sao Paulo General Hospital · FDA-approved active Small molecule Quality 2/100

1 ampoule of Hylan GF-20 is a Small molecule drug developed by University of Sao Paulo General Hospital. It is currently FDA-approved. Also known as: 1 ampole of Synvisc Classic.

Hylan GF-20, marketed by the University of Sao Paulo General Hospital, is a viscosupplement used in the treatment of osteoarthritis, currently holding a position in the competitive landscape. The drug's key strength lies in its key composition patent, which is set to expire in 2028, providing a period of market exclusivity. The primary risk is the potential increase in competition following the patent expiry, which could impact revenue.

At a glance

Generic name	1 ampoule of Hylan GF-20
Also known as	1 ampole of Synvisc Classic
Sponsor	University of Sao Paulo General Hospital
Modality	Small molecule
Phase	FDA-approved

Approved indications

No approved indications tracked.

Common side effects

No common side effects on file.

Key clinical trials

Hip Viscosupplementation: What is the Best Dosage? (PHASE4)

Primary sources

Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.

Source	Used for
ClinicalTrials.gov	Trial enrolment, design, endpoints, results

Competitive intelligence

For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:

1 ampoule of Hylan GF-20 CI brief — competitive landscape report
1 ampoule of Hylan GF-20 updates RSS · CI watch RSS
University of Sao Paulo General Hospital portfolio CI

Frequently asked questions about 1 ampoule of Hylan GF-20

What is 1 ampoule of Hylan GF-20?

1 ampoule of Hylan GF-20 is a Small molecule drug developed by University of Sao Paulo General Hospital.

Who makes 1 ampoule of Hylan GF-20?

1 ampoule of Hylan GF-20 is developed and marketed by University of Sao Paulo General Hospital (see full University of Sao Paulo General Hospital pipeline at /company/university-of-sao-paulo-general-hospital).

Is 1 ampoule of Hylan GF-20 also known as anything else?

1 ampoule of Hylan GF-20 is also known as 1 ampole of Synvisc Classic.

What development phase is 1 ampoule of Hylan GF-20 in?

1 ampoule of Hylan GF-20 is FDA-approved (marketed).

Manufacturer: University of Sao Paulo General Hospital — full pipeline
Also known as: 1 ampole of Synvisc Classic
Compare: 1 ampoule of Hylan GF-20 vs similar drugs
Pricing: 1 ampoule of Hylan GF-20 cost, discount & access